Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11143127 | 0.92 | L3MBTL1 (0.59) | L3MBTL1LMNAKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL11150764 | 0.88 | L3MBTL1 (0.55) | L3MBTL1LMNAKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL11148675 | 0.88 | L3MBTL1 (0.52) | L3MBTL1LMNAKMT2AP2RX7ALDH1A1 | |
| SCHEMBL11146311 | 0.86 | GRM5 (0.42) | L3MBTL1KMT2AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL11151463 | 0.82 | L3MBTL1 (0.48) | L3MBTL1LMNAKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL11146807 | 0.81 | L3MBTL1 (0.47) | L3MBTL1LMNAKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL11146421 | 0.81 | L3MBTL1 (0.45) | L3MBTL1LMNAKMT2AP2RX7ALDH1A1 | |
| SCHEMBL10993445 | 0.80 | GRM5 (0.45) | KMT2AALDH1A1MAPTGRM5 | |
| SCHEMBL11148554 | 0.79 | L3MBTL1 (0.46) | L3MBTL1LMNAKMT2AALDH1A1EGFR | |
| SCHEMBL11141810 | 0.78 | L3MBTL1 (0.45) | L3MBTL1KMT2AALDH1A1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4402964-A | N-Aryl-N'-(3-methyl or ethyl-4-oxothiazolidinylidene)ureas useful for the treatment of epilepsy | MCNEILAB, INC. (US) | 1983-09-06 | — | — | US | disclosed |