Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10994616 | 0.92 | GRM5 (0.49) | GRM5GAAMAPTKDM4EPOLB | |
| SCHEMBL10994165 | 0.88 | GRM5 (0.46) | GRM5GAAPOLBNLRP3 | |
| SCHEMBL10992667 | 0.87 | GRM5 (0.43) | GRM5TDP1POLB | |
| SCHEMBL10992614 | 0.85 | GRM5 (0.61) | GRM5GAADGAT1MAPTKDM4E | |
| SCHEMBL10998809 | 0.82 | GRM5 (0.45) | GRM5GAAMAPTTDP1KDM4E | |
| SCHEMBL10993280 | 0.81 | GRM5 (0.44) | GRM5GAAMAPTKDM4EPOLB | |
| SCHEMBL10994318 | 0.80 | GRM5 (0.42) | GRM5GAAMAPTKDM4EPOLB | |
| SCHEMBL11148694 | 0.80 | L3MBTL1 (0.54) | GRM5MAPTALDH1A1KMT2A | |
| SCHEMBL10994147 | 0.79 | ALDH1A1 (0.43) | GRM5GAAMAPTKDM4EALDH1A1 | |
| SCHEMBL10998555 | 0.78 | NLRP3 (0.44) | GRM5MAPTTDP1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4542144-A | EPILEPSY | MCNEILAB INC. (US) | 1985-09-17 | — | — | US | disclosed |