SCHEMBL11149002

SCHEMBL11149002

CC1(C)CC(C(=O)c2ccccc2)CC(C)(C)N1O

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.47
MAPT P10636 1/20 0.47
GAA P10253 3/20 0.43
KDM4E B2RXH2 2/20 0.43
ALDH1A1 P00352 1/20 0.42
ALOX15 P16050 1/20 0.42
TSHR P16473 2/20 0.41
KCNH2 Q12809 1/20 0.41
HTR2A P28223 1/20 0.41
CPB1 P15086 1/20 0.41
MEN1 O00255 2/20 0.40
HTT P42858 1/20 0.40
MGLL Q99685 1/20 0.40
HSD11B1 P28845 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11148998 0.86 SLC18A3 (0.42) KMT2AGAATSHRKCNH2HTR2A
SCHEMBL28166608 0.83 KMT2A (0.40) KMT2ATSHRKCNH2HTR2ACPB1
SCHEMBL11638759 0.82 ALDH1A1 (0.39) KMT2AGAAALDH1A1TSHRKCNH2
SCHEMBL10430917 0.77 KMT2A (0.50) KMT2AMAPTGAAALDH1A1TSHR
SCHEMBL40016 0.77 GAA (0.59) KMT2AMAPTGAAKDM4EALDH1A1
SCHEMBL6723861 0.76 KMT2A (0.43) KMT2AGAAALDH1A1TSHRKCNH2
SCHEMBL25888341 0.76 MGLL (0.44) KMT2AMAPTALDH1A1ALOX15TSHR
SCHEMBL18770952 0.76 ELANE (0.45) KMT2AMAPTGAAKDM4EALDH1A1
SCHEMBL243559 0.76 TSHR (0.70) KMT2AMAPTGAAALDH1A1TSHR
SCHEMBL3916706 0.76 KDM4E (0.72) KMT2AGAAKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2146360-B1 SEALING MATERIAL FOR ELECTROLYTIC CAPACITOR AND ELECTROLYTIC CAPACITOR EMPLOYING THE SEALING MATERIAL NIPPON CHEMICON (JP) 2013-02-20 EP disclosed
US-8310813-B2 Sealing material for electrolytic capacitor and electrolytic capacitor employing the sealing material NIPPON CHEMI-CON CORPORATION (JP) 2012-11-13 US disclosed
US-8310813-B2 Sealing material for electrolytic capacitor and electrolytic capacitor employing the sealing material NIPPON CHEMI-CON CORPORATION (JP) 2012-11-13 US disclosed
US-7956134-B2 Modified by a nitroxide-free radical stable in the presence of oxygen at an ordinary temperature (a 2,2,6,6-tetramethyl piperidinyloxy derivative) and an organic peroxide crosslinking agent; improved cost efficiency; high tensile properties THE YOKOHAMA RUBBER CO., LTD. (JP) 2011-06-07 US disclosed
US-7812096-B2 Modification method of polymer THE YOKOHAMA RUBBER CO., LTD. (JP) 2010-10-12 US disclosed
US-7772325-B2 Thermoplastic elastomer composition THE YOKOHAMA RUBBER CO., LTD. (JP) 2010-08-10 US disclosed
US-20100056723-A1 THERMOPLASTIC ELASTOMER COMPOSITION THE YOKOHAMA RUBBER CO., LTD. (JP) 2010-03-04 US disclosed
EP-2146360-A1 SEALING MATERIAL FOR ELECTROLYTIC CAPACITOR AND ELECTROLYTIC CAPACITOR EMPLOYING THE SEALING MATERIAL NIPPON CHEMI-CON CORPORATION (JP) 2010-01-20 EP disclosed
US-7589155-B2 Modified butyl rubber composition THE YOKOHAMA RUBBER CO., LTD. (JP) 2009-09-15 US disclosed
US-20090156728-A1 MODIFIED BUTYL RUBBER COMPOSITION THE YOKOHAMA RUBBER CO., LTD. (JP) 2009-06-18 US disclosed
US-20080207845-A1 Method For Producing Modified Polymer And Modified Polymer Produced By The Same THE YOKOHAMA RUBBER CO., LTD. (JP) 2008-08-28 US disclosed
US-20080146737-A1 THERMOPLASTIC ELASTOMER COMPOSITION THE YOKOHAMA RUBBER CO., LTD. (JP) 2008-06-19 US disclosed
US-7282542-B2 Modification method of polymer THE YOKOHAMA RUBBER CO., LTD. (JP) 2007-10-16 US disclosed
EP-1837350-A1 PROCESS FOR PRODUCTION OF MODIFIED POLYMERS AND MODIFIED POLYMERS PRODUCED THEREBY THE YOKOHAMA RUBBER CO., LTD. (JP) 2007-09-26 EP disclosed
US-20070093607-A1 Modified butyl rubber composition THE YOKOHAMA RUBBER CO., LTD. (JP) 2007-04-26 US disclosed
EP-1777237-A1 Modified butyl rubber composition The Yokohama Rubber Co., Ltd. (JP) 2007-04-25 EP disclosed
US-4396735-A N-HETEROCYCLIC COMPOUND AND A HETEROCYCLIC ACID HYDRAZIDE ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1983-08-02 US disclosed
US-4362831-A A HINDERED AND HETEROCYCLIC AMINE WITH A THIOALKANOIC ACID AMIDE ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1982-12-07 US disclosed
US-4123418-A BIS-(U8I8I8L8L-PENTAMETHY TETRAMETHYL-4-PIPERIDYL)-SUBERATE CIBA-GEIGY CORPORATION (US) 1978-10-31 US disclosed
US-4110304-A STERICALLY HINDERED CYCLIC AMINE CIBA-GEIGY CORPORATION (US) 1978-08-29 US disclosed