SCHEMBL28166608

SCHEMBL28166608

CC1(C)CC(C(=O)c2ccccc2)CC(C)(C)N1c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.40
MEN1 O00255 3/20 0.40
LMNA P02545 2/20 0.40
TSHR P16473 2/20 0.40
KCNH2 Q12809 1/20 0.40
PKM P14618 1/20 0.39
HTT P42858 1/20 0.39
HTR2A P28223 1/20 0.39
CPB1 P15086 1/20 0.39
MGLL Q99685 1/20 0.38
HSD11B1 P28845 1/20 0.38
NPC1 O15118 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
MCL1 Q07820 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11148998 0.83 SLC18A3 (0.42) KMT2AMEN1TSHRKCNH2HTR2A
SCHEMBL11149002 0.83 KMT2A (0.47) KMT2AMEN1TSHRKCNH2HTT
SCHEMBL11638759 0.79 ALDH1A1 (0.39) KMT2AMEN1TSHRKCNH2HTR2A
SCHEMBL28108099 0.77 TSHR (0.67) KMT2AMEN1LMNATSHRHTT
SCHEMBL12589187 0.75 ALDH1A1 (0.37) KMT2AMEN1TSHR
SCHEMBL10430917 0.75 KMT2A (0.50) KMT2AMEN1LMNATSHRKCNH2
SCHEMBL40016 0.75 GAA (0.59) KMT2AMEN1LMNATSHRPKM
SCHEMBL6905310 0.74 KMT2A (0.49) KMT2AMEN1LMNATSHRHTT
SCHEMBL6723861 0.74 KMT2A (0.43) KMT2ALMNATSHRKCNH2HTR2A
SCHEMBL25888341 0.73 MGLL (0.44) KMT2AMEN1TSHRHTTHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107001698-A Phosphorous organic epoxide acid imide is used as flame retardant of plastic agent and/or the purposes of stabilizer, fire-retardant and/or stable plastics composite, its preparation method, molded item, paint and coating 弗劳恩霍弗应用研究促进协会 2017-08-01 CN disclosed