Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | SETDB1 | Q15047 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27345420 | 0.78 | ALDH1A1 (0.41) | SMN1; SMN2KDM4ENPC1MAPTRAB9A | |
| SCHEMBL11389449 | 0.76 | GAA (0.38) | MAPT | |
| Hydrochloric Acid SCHEMBL8805169 | 0.74 | GAA (0.36) | MAPT | |
| SCHEMBL29133228 | 0.73 | KDM4E (0.38) | SMN1; SMN2KDM4ENPC1MAPTRAB9A | |
| SCHEMBL28831505 | 0.73 | GAA (0.39) | MAPT | |
| SCHEMBL9540291 | 0.73 | HRH4 (0.38) | SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL9789197 | 0.72 | GAA (0.38) | NPC1MAPT | |
| SCHEMBL9527218 | 0.72 | GAA (0.38) | MAPT | |
| SCHEMBL11143948 | 0.71 | — | — | |
| SCHEMBL8638648 | 0.71 | MAPT (0.37) | KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4382030-A | ANALGESICS; DIURETICS; ANTIARRHYTHMIC AND BRONCHODILATOR AGENTS; SEDATIVES; PSYCHOLOGICAL DISORDERS | KALI-CHEMIE PHARMA GMBH (DE) | 1983-05-03 | — | — | US | disclosed |