Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HSPB1 | P04792 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TTR | P02766 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11665258 | 0.93 | KMT2A (0.48) | KMT2AMEN1MAPTLMNAKDM4E | |
| SCHEMBL11665102 | 0.91 | L3MBTL1 (0.49) | KMT2AMEN1MAPTLMNAKDM4E | |
| SCHEMBL11154930 | 0.91 | ALDH1A1 (0.52) | KMT2AMEN1MAPTLMNAKDM4E | |
| SCHEMBL11665361 | 0.89 | KMT2A (0.44) | KMT2AMEN1MAPTLMNAKDM4E | |
| SCHEMBL11664180 | 0.89 | KMT2A (0.44) | KMT2AMEN1MAPTLMNAKDM4E | |
| SCHEMBL11665833 | 0.89 | KMT2A (0.46) | KMT2AMEN1MAPTLMNAKDM4E | |
| SCHEMBL11664059 | 0.88 | MAPT (0.49) | KMT2AMEN1MAPTLMNAKDM4E | |
| SCHEMBL11665359 | 0.88 | KMT2A (0.47) | KMT2AMEN1MAPTLMNAKDM4E | |
| SCHEMBL7907598 | 0.87 | MEN1 (0.48) | KMT2AMEN1MAPTLMNAKDM4E | |
| SCHEMBL11665104 | 0.85 | NPC1 (0.51) | KMT2AMEN1MAPTLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0036591-B1 | COUPLER COMPONENTS FOR OXIDATION HAIR DYES, THEIR PREPARATION AND USE, AND HAIR DYES CONTAINING THEM | Henkel Kommanditgesellschaft auf Aktien (DE) | 1983-11-16 | — | — | EP | disclosed |
| US-4371370-A | Oxidation hair dyes comprising bis-(2,4-diaminophenoxy)-alkanols as coupling components | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1983-02-01 | — | — | US | disclosed |
| EP-0036591-A1 | Coupler components for oxidation hair dyes, their preparation and use, and hair dyes containing them | Henkel Kommanditgesellschaft auf Aktien (DE) | 1981-09-30 | — | — | EP | disclosed |