Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | TTR | P02766 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HSPB1 | P04792 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11149431 | 0.93 | KMT2A (0.51) | KMT2AMEN1MAPTTTRLMNA | |
| SCHEMBL11665102 | 0.87 | L3MBTL1 (0.49) | KMT2AMEN1MAPTTTRLMNA | |
| SCHEMBL11154930 | 0.87 | ALDH1A1 (0.52) | KMT2AMEN1MAPTTTRLMNA | |
| SCHEMBL11665294 | 0.86 | MEN1 (0.46) | KMT2AMEN1MAPTTTRLMNA | |
| SCHEMBL9794575 | 0.86 | GPR35 (0.45) | KMT2AMEN1TTRLMNAKDM4E | |
| SCHEMBL19009004 | 0.84 | TTR (0.50) | KMT2AMEN1MAPTTTRLMNA | |
| SCHEMBL13172174 | 0.84 | S1PR4 (0.49) | KMT2AMEN1LMNAKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL10417398 | 0.84 | GPR35 (0.44) | KMT2AMEN1TTRLMNAKDM4E | |
| SCHEMBL11664059 | 0.84 | MAPT (0.49) | KMT2AMEN1MAPTTTRLMNA | |
| SCHEMBL11665359 | 0.84 | KMT2A (0.47) | KMT2AMEN1MAPTTTRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4123614-A | USED IN DETECTION AND MEASUREMENT OF BIOLOGICAL SYSTEMS AND/OR COMPONENTS | SYNTEX (U.S.A.) INC. (US) | 1978-10-31 | — | — | US | disclosed |