Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 11/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1115287 | 0.91 | RECQL (0.38) | PTGS2PTGS1ALOX5KMT2A | |
| SCHEMBL1115143 | 0.91 | PTGS2 (0.38) | PTGS2PTGS1KMT2AMAPT | |
| SCHEMBL1115189 | 0.89 | PTGS2 (0.40) | PTGS2PTGS1 | |
| SCHEMBL1115172 | 0.88 | PTGS2 (0.42) | PTGS2PTGS1TP53HTT | |
| SCHEMBL1114989 | 0.88 | KMT2A (0.42) | PTGS2PTGS1KMT2AMAPT | |
| SCHEMBL1115111 | 0.86 | PTGS2 (0.50) | PTGS2PTGS1MAPT | |
| SCHEMBL1115052 | 0.84 | PTGS1 (0.45) | PTGS2PTGS1KMT2AMAPTHTT | |
| SCHEMBL1115174 | 0.84 | HSD11B1 (0.39) | PTGS2PTGS1KMT2A | |
| SCHEMBL1115012 | 0.84 | PTGS2 (0.39) | PTGS2PTGS1KMT2AMAPT | |
| SCHEMBL1115324 | 0.84 | PTGS2 (0.43) | PTGS2PTGS1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567508-B1 | 1,2,4-TRIAZOLE DERIVATIVE, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | CJ CHEILJEDANG CORP (KR) | 2011-02-02 | — | — | EP | disclosed |
| EP-1567508-B1 | 1,2,4-TRIAZOLE DERIVATIVE, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | CJ CHEILJEDANG CORP (KR) | 2011-02-02 | — | — | EP | disclosed |
| EP-1567508-A4 | 1,2,4-TRIAZOLE DERIVATIVE, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | CJ CHEILJEDANG CORP (KR) | 2008-12-10 | — | — | EP | disclosed |
| EP-1567508-A1 | 1,2,4-TRIAZOLE DERIVATIVE, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | CJ Corporation (KR) | 2005-08-31 | — | — | EP | disclosed |
| US-6849652-B1 | 1,2,4-triazole derivative, method for preparing the same, and pharmaceutical composition containing the same | CJ CORP. (KR) | 2005-02-01 | — | — | US | disclosed |
| WO-2004046121-A1 | 1,2,4-TRIAZOLE DERIVATIVE, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | CJ CORPORATION (KR) | 2004-06-03 | — | — | WO | disclosed |