Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1115012 | 0.91 | PTGS2 (0.39) | KMT2AALDH1A1PTGS1PTGS2MAPT | |
| SCHEMBL1115143 | 0.90 | PTGS2 (0.38) | KMT2ASMN1; SMN2PTGS1PTGS2MAPT | |
| SCHEMBL1115287 | 0.90 | RECQL (0.38) | KMT2ASMN1; SMN2PTGS1PTGS2 | |
| SCHEMBL1115198 | 0.90 | PTGS2 (0.40) | KMT2AKDM4EHSD17B10PTGS1PTGS2 | |
| SCHEMBL1115174 | 0.89 | HSD11B1 (0.39) | KMT2AALDH1A1SMN1; SMN2PTGS1PTGS2 | |
| SCHEMBL1115172 | 0.88 | PTGS2 (0.42) | PTGS1PTGS2 | |
| SCHEMBL1114969 | 0.88 | PTGS2 (0.36) | KMT2APTGS1PTGS2MAPT | |
| SCHEMBL1115302 | 0.88 | PTGS2 (0.41) | KMT2AHPGDSMN1; SMN2PTGS1PTGS2 | |
| SCHEMBL1115189 | 0.87 | PTGS2 (0.40) | ALDH1A1PTGS1PTGS2 | |
| SCHEMBL1115111 | 0.86 | PTGS2 (0.50) | HPGDHSD17B10PTGS1PTGS2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567508-B1 | 1,2,4-TRIAZOLE DERIVATIVE, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | CJ CHEILJEDANG CORP (KR) | 2011-02-02 | — | — | EP | disclosed |
| EP-1567508-B1 | 1,2,4-TRIAZOLE DERIVATIVE, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | CJ CHEILJEDANG CORP (KR) | 2011-02-02 | — | — | EP | disclosed |
| US-6849652-B1 | 1,2,4-triazole derivative, method for preparing the same, and pharmaceutical composition containing the same | CJ CORP. (KR) | 2005-02-01 | — | — | US | disclosed |