Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.45 |
| ▸ | SOAT2 | O75908 | 3/20 | 0.43 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | CASP7 | P55210 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11153753 | 0.86 | MAPT (0.43) | TP53ALDH1A1KDM4EHPGDCASP1 | |
| SCHEMBL11149532 | 0.72 | KDM4E (0.51) | TP53ALDH1A1KDM4EHPGDMAPK1 | |
| SCHEMBL11151333 | 0.72 | MAPT (0.39) | TP53ALDH1A1KDM4EHPGDRXFP1 | |
| SCHEMBL11342500 | 0.72 | KMT2A (0.43) | EP300SOAT2SOAT1TP53ALDH1A1 | |
| SCHEMBL11342323 | 0.70 | THRB (0.37) | TP53ALDH1A1KDM4ECASP1CASP7 | |
| SCHEMBL27622427 | 0.67 | MAPT (0.77) | ALDH1A1KDM4EMAPK1SMN1; SMN2MAPT | |
| SCHEMBL20369717 | 0.67 | MAPT (0.77) | ALDH1A1KDM4EMAPK1SMN1; SMN2MAPT | |
| SCHEMBL28937884 | 0.66 | SMN1; SMN2 (0.61) | EP300ALDH1A1KDM4EHPGDGAA | |
| SCHEMBL24052759 | 0.66 | TLR8 (0.86) | EP300ALDH1A1KDM4EHPGDGAA | |
| SCHEMBL3777911 | 0.66 | SMN1; SMN2 (0.68) | EP300SOAT2SOAT1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0005357-B1 | N-(BENZOTHIENOPYRAZOL)-AMIDES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-02-09 | — | — | EP | disclosed |
| EP-0005357-A1 | N-(Benzothienopyrazol)-amides and pharmaceutical compositions containing them | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-11-14 | — | — | EP | disclosed |
| US-4140785-A | N-(benzothienopyrazol)amide antirhinoviral agents | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-02-20 | — | — | US | disclosed |