Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 7/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | G6PD | P11413 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11149916 | 0.82 | TP53 (0.39) | MAPTALDH1A1KDM4ERXFP1RAB9A | |
| SCHEMBL11153276 | 0.81 | MAPT (0.40) | MAPTALDH1A1KDM4ERXFP1RAB9A | |
| SCHEMBL11149542 | 0.80 | PARP14 (0.47) | MAPTALDH1A1KDM4ERXFP1RAB9A | |
| SCHEMBL11153753 | 0.77 | MAPT (0.43) | MAPTALDH1A1KDM4ERXFP1RAB9A | |
| SCHEMBL11216887 | 0.77 | ALDH1A1 (0.48) | MAPTALDH1A1KDM4ERXFP1RAB9A | |
| SCHEMBL11155492 | 0.76 | TP53 (0.41) | MAPTALDH1A1KDM4ERXFP1TP53 | |
| SCHEMBL11147960 | 0.76 | ALDH1A1 (0.38) | MAPTALDH1A1KDM4ERXFP1RAB9A | |
| SCHEMBL11144647 | 0.75 | RAB9A (0.43) | MAPTALDH1A1RAB9AHPGDTP53 | |
| SCHEMBL11150491 | 0.73 | HSD17B10 (0.41) | MAPTALDH1A1KDM4ERXFP1RAB9A | |
| SCHEMBL11148719 | 0.72 | KDM4E (0.43) | MAPTALDH1A1KDM4ERAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0005357-B1 | N-(BENZOTHIENOPYRAZOL)-AMIDES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-02-09 | — | — | EP | disclosed |