Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 10/20 | 0.74 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.74 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.74 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.74 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.74 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.74 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.74 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.74 |
| ▸ | HTR3A | P46098 | 2/20 | 0.53 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12233993 | 0.91 | SLC6A2 (0.72) | SLC6A2SLC6A4OPRM1OPRK1OPRD1 | |
| SCHEMBL11155426 | 0.91 | SLC6A2 (0.72) | SLC6A2SLC6A4OPRM1OPRK1OPRD1 | |
| SCHEMBL15920337 | 0.87 | SLC6A2 (0.81) | SLC6A2SLC6A4OPRM1OPRK1OPRD1 | |
| (R,R)-Tramadol SCHEMBL405854 | 0.87 | SLC6A2 (0.98) | SLC6A2SLC6A4OPRM1OPRK1OPRD1 | |
| (R,R)-Tramadol SCHEMBL429520 | 0.87 | SLC6A2 (0.98) | SLC6A2SLC6A4OPRM1OPRK1OPRD1 | |
| (R,R)-Tramadol SCHEMBL7141021 | 0.87 | SLC6A2 (0.98) | SLC6A2SLC6A4OPRM1OPRK1OPRD1 | |
| (R,R)-Tramadol SCHEMBL7137387 | 0.87 | SLC6A2 (0.98) | SLC6A2SLC6A4OPRM1OPRK1OPRD1 | |
| (R,R)-Tramadol SCHEMBL41748 | 0.87 | SLC6A2 (0.98) | SLC6A2SLC6A4OPRM1OPRK1OPRD1 | |
| (R,R)-Tramadol SCHEMBL1377516 | 0.87 | SLC6A2 (0.98) | SLC6A2SLC6A4OPRM1OPRK1OPRD1 | |
| Tramadol SCHEMBL405855 | 0.87 | SLC6A2 (0.98) | SLC6A2SLC6A4OPRM1OPRK1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0010717-B1 | 6,7-CYCLOALKANO-1,4-OXAZEPINES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1983-09-21 | — | — | EP | disclosed |
| US-4336263-A | 1,4-Cycloalkano-oxazepines, salts thereof and analgesic uses thereof | BASF AKTIENGESELLSCHAFT (DE) | 1982-06-22 | — | — | US | disclosed |
| EP-0020515-A1 | NOVEL 1,4-CYCLO-ALKANO-OXAZEPINES,THEIR PROCESS OF MANUFACTURE, PHARMACEUTICALS CONTAINING THEM AND THEIR UTILISATION | BASF Aktiengesellschaft (DE) | 1981-01-07 | — | — | EP | disclosed |
| EP-0010717-A1 | 6,7-Cycloalkano-1,4-oxazepines, process for their preparation and medicines containing them | BASF Aktiengesellschaft (DE) | 1980-05-14 | — | — | EP | disclosed |
| WO-1980000838-A1 | NOVEL 1,4-CYCLO-ALKANO-OXAZEPINES,THEIR PROCESS OF MANUFACTURE,PHARMACEUTICALS CONTAINING THEM AND THEIR UTILISATION | BASF AG (DE) | 1980-05-01 | — | — | WO | disclosed |