Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GRM5 | P41594 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CLK1 | P49759 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11146126 | 0.93 | RIPK1 (0.40) | MEN1KMT2AGRM5ALDH1A1GAA | |
| SCHEMBL11148292 | 0.93 | L3MBTL1 (0.41) | MEN1KMT2AGRM5ALDH1A1GAA | |
| SCHEMBL11147044 | 0.92 | MEN1 (0.39) | MEN1KMT2AGRM5ALDH1A1GAA | |
| SCHEMBL11146421 | 0.85 | L3MBTL1 (0.45) | KMT2AALDH1A1TSHRMAPTMAPK1 | |
| SCHEMBL11149198 | 0.84 | KMT2A (0.45) | MEN1KMT2AGRM5ALDH1A1GAA | |
| SCHEMBL11149203 | 0.84 | KMT2A (0.45) | MEN1KMT2AGRM5ALDH1A1GAA | |
| SCHEMBL11147166 | 0.83 | KMT2A (0.46) | MEN1KMT2AGRM5ALDH1A1GAA | |
| SCHEMBL11147165 | 0.83 | KMT2A (0.46) | MEN1KMT2AGRM5ALDH1A1GAA | |
| SCHEMBL11155555 | 0.81 | GRM5 (0.46) | MEN1KMT2AGRM5ALDH1A1GAA | |
| SCHEMBL11143146 | 0.81 | MEN1 (0.45) | MEN1KMT2AGRM5ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4402964-A | N-Aryl-N'-(3-methyl or ethyl-4-oxothiazolidinylidene)ureas useful for the treatment of epilepsy | MCNEILAB, INC. (US) | 1983-09-06 | — | — | US | disclosed |