Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11147165 | 1.00 | KMT2A (0.46) | KMT2AMEN1PSMD14GAAALDH1A1 | |
| SCHEMBL11141779 | 0.92 | GRM5 (0.42) | KMT2AMEN1PSMD14GAAALDH1A1 | |
| SCHEMBL11144521 | 0.92 | GRM5 (0.42) | KMT2AMEN1PSMD14GAAALDH1A1 | |
| SCHEMBL11144882 | 0.90 | ALDH1A1 (0.45) | KMT2AMEN1PSMD14ALDH1A1NPSR1 | |
| SCHEMBL11146126 | 0.89 | RIPK1 (0.40) | KMT2AMEN1PSMD14GAAALDH1A1 | |
| SCHEMBL11143146 | 0.86 | MEN1 (0.45) | KMT2AMEN1PSMD14GAAALDH1A1 | |
| SCHEMBL11149203 | 0.86 | KMT2A (0.45) | KMT2AMEN1GAAALDH1A1NPSR1 | |
| SCHEMBL11155555 | 0.86 | GRM5 (0.46) | KMT2AMEN1GAAALDH1A1NPSR1 | |
| SCHEMBL11143150 | 0.86 | MEN1 (0.45) | KMT2AMEN1PSMD14GAAALDH1A1 | |
| SCHEMBL11155554 | 0.86 | GRM5 (0.46) | KMT2AMEN1GAAALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4402964-A | N-Aryl-N'-(3-methyl or ethyl-4-oxothiazolidinylidene)ureas useful for the treatment of epilepsy | MCNEILAB, INC. (US) | 1983-09-06 | — | — | US | claimed |
| US-4402964-A | N-Aryl-N'-(3-methyl or ethyl-4-oxothiazolidinylidene)ureas useful for the treatment of epilepsy | MCNEILAB, INC. (US) | 1983-09-06 | — | — | US | disclosed |