SCHEMBL11151925

SCHEMBL11151925

CCC(C#N)c1cccc(SC(F)(F)F)c1

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.33
CETP P11597 2/20 0.32
RXFP1 Q9HBX9 1/20 0.32
TAAR1 Q96RJ0 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11167652 0.81 ALDH1A1 (0.40) AR
SCHEMBL24781619 0.78 HDAC4 (0.45) CETPRXFP1SMN1; SMN2
SCHEMBL11166250 0.78 ESR1 (0.36) ARCETPTAAR1SMN1; SMN2
SCHEMBL10928359 0.77 TSHR (0.47) ARCETPRXFP1
SCHEMBL958288 0.77 PNMT (0.47) SMN1; SMN2
SCHEMBL29061977 0.74 AOC3 (0.40)
SCHEMBL954467 0.74 AOC3 (0.40)
SCHEMBL12610671 0.74 ALDH1A1 (0.41) CETPRXFP1SMN1; SMN2
SCHEMBL4138269 0.73 ALDH1A1 (0.44) TAAR1
SCHEMBL11157146 0.72 AKR1C3 (0.47) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4405639-A INSECTICIDES; PESTICIDES; MITICIDES; NEMATOCIDES; PARACITICIDES BAYER AKTIENGESELLSCHAFT (DE) 1983-09-20 US disclosed
US-4348323-A FLUORINE-CONTAINING BENZODIOXINE INSECTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1982-09-07 US disclosed
US-4284643-A Combating arthropods with novel fluorine-containing phenylacetic acid esters BAYER AKTIENGESELLSCHAFT (DE) 1981-08-18 US disclosed