Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARK7 | Q99497 | 3/20 | 0.49 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 4/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.43 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.43 |
| ▸ | CDC25A | P30304 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11150483 | 0.88 | PARK7 (0.63) | PARK7NSD2ALDH1A1ALDH3A1CHRM5 | |
| SCHEMBL7833229 | 0.78 | PARK7 (0.67) | PARK7NSD2ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL28547209 | 0.78 | PARK7 (0.71) | PARK7NSD2CES1ALDH1A1ALDH2 | |
| SCHEMBL2149622 | 0.78 | CES1 (0.73) | PARK7CES1BCHEALDH1A1ALDH2 | |
| SCHEMBL28547202 | 0.76 | PARK7 (0.69) | PARK7NSD2CES1ALDH1A1ALDH2 | |
| SCHEMBL28546572 | 0.76 | PARK7 (0.69) | PARK7NSD2CES1ALDH1A1ALDH2 | |
| SCHEMBL28539851 | 0.76 | PARK7 (0.69) | PARK7NSD2CES1ALDH1A1ALDH2 | |
| SCHEMBL28533459 | 0.76 | PARK7 (0.69) | PARK7NSD2CES1ALDH1A1ALDH2 | |
| SCHEMBL12930212 | 0.76 | ALDH1A1 (0.67) | PARK7CES1BCHEALDH1A1ALDH2 | |
| SCHEMBL18954583 | 0.75 | ALDH1A1 (0.47) | PARK7CES1ALDH1A1ALDH2ALDH3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4382934-A | ANTIALLERGENS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-05-10 | — | — | US | disclosed |
| EP-0010398-B1 | ISATIN DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-04-27 | — | — | EP | disclosed |
| EP-0010398-A1 | Isatin derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-04-30 | — | — | EP | disclosed |