Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10761962 | 0.95 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2LMNAGAAPKM | |
| SCHEMBL17789122 | 0.88 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2LMNAGAAPKM | |
| SCHEMBL1105205 | 0.88 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2LMNAGAAPKM | |
| SCHEMBL20489942 | 0.87 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2LMNAGAAPKM | |
| SCHEMBL20489943 | 0.87 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2LMNAGAAPKM | |
| SCHEMBL15120914 | 0.85 | LMNA (0.44) | ALDH1A1SMN1; SMN2LMNAGAAPKM | |
| SCHEMBL15110982 | 0.85 | LMNA (0.44) | ALDH1A1SMN1; SMN2LMNAGAAPKM | |
| SCHEMBL11184528 | 0.85 | CA2 (0.44) | ALDH1A1LMNAGAACA9BCHE | |
| SCHEMBL2058187 | 0.85 | GAA (0.42) | ALDH1A1SMN1; SMN2GAAPKMCA9 | |
| SCHEMBL9575873 | 0.84 | LMNA (0.40) | ALDH1A1SMN1; SMN2LMNAGAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4393240-A | BIS(DIPHENYPHOSPHINO) PROPANE DERIVATIVES FOR MAKING RHODIUM COMPLEX CATALYSTS | STILLE JOHN K | 1983-07-12 | — | — | US | claimed |
| US-4393240-A | BIS(DIPHENYPHOSPHINO) PROPANE DERIVATIVES FOR MAKING RHODIUM COMPLEX CATALYSTS | STILLE JOHN K | 1983-07-12 | — | — | US | disclosed |