Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 9/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 7/20 | 0.64 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.64 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.64 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.64 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | HTR1A | P08908 | 3/20 | 0.64 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.64 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.64 |
| ▸ | DRD3 | P35462 | 2/20 | 0.64 |
| ▸ | HTR2B | P41595 | 2/20 | 0.64 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL10651729 | 0.96 | ADRB2 (0.65) | ADRB2ADRA1AADRB1ADRA1DADRA1B | |
| Sulfinalol SCHEMBL29387627 | 0.87 | SLC6A4 (0.66) | ADRB2ADRA1AADRB1ADRA1DADRA1B | |
| Sulfinalol SCHEMBL6510272 | 0.87 | SLC6A4 (0.66) | ADRB2ADRA1AADRB1ADRA1DADRA1B | |
| SCHEMBL11191842 | 0.87 | ADRB2 (0.52) | ADRB2ADRA1AADRB1ADRA1DADRA1B | |
| Sulfinalol SCHEMBL78008 | 0.87 | SLC6A4 (0.66) | ADRB2ADRA1AADRB1ADRA1DADRA1B | |
| Sulfinalol SCHEMBL29918144 | 0.86 | ADRA1A (0.65) | ADRB2ADRA1AADRB1ADRA1DADRA1B | |
| SCHEMBL11199965 | 0.86 | ADRB2 (0.48) | ADRB2ADRA1AADRB1ADRA1DADRA1B | |
| Sulfinalol SCHEMBL121669 | 0.86 | ADRA1A (0.65) | ADRB2ADRA1AADRB1ADRA1DADRA1B | |
| Sulfinalol SCHEMBL1650838 | 0.86 | SLC6A4 (0.64) | ADRB2ADRA1AADRB1ADRA1DADRA1B | |
| SCHEMBL11372676 | 0.83 | ADRB2 (0.58) | ADRB2ADRA1AADRB1ADRA1DADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4374149-A | HYPOTENSIVE AGENT AND VASODILATOR | STERLING DRUG INC. (US) | 1983-02-15 | — | — | US | claimed |