Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.66 |
| ▸ | HTR1A | P08908 | 2/20 | 0.66 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.66 |
| ▸ | ADRB2 | P07550 | 16/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 9/20 | 0.56 |
| ▸ | ADRB3 | P13945 | 7/20 | 0.56 |
| ▸ | DRD2 | P14416 | 2/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | DRD3 | P35462 | 2/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfinalol SCHEMBL29387627 | 1.00 | SLC6A4 (0.66) | SLC6A4ADRA1AHTR1ASLC6A2ADRB2 | |
| Sulfinalol SCHEMBL78008 | 1.00 | SLC6A4 (0.66) | SLC6A4ADRA1AHTR1ASLC6A2ADRB2 | |
| Sulfinalol SCHEMBL29918144 | 0.99 | ADRA1A (0.65) | SLC6A4ADRA1AHTR1ASLC6A2ADRB2 | |
| Sulfinalol SCHEMBL121669 | 0.99 | ADRA1A (0.65) | SLC6A4ADRA1AHTR1ASLC6A2ADRB2 | |
| Sulfinalol SCHEMBL1650838 | 0.98 | SLC6A4 (0.64) | SLC6A4ADRA1AHTR1ASLC6A2ADRB2 | |
| SCHEMBL9548061 | 0.90 | SLC6A4 (0.58) | SLC6A4ADRA1AHTR1ASLC6A2ADRB2 | |
| SCHEMBL11193698 | 0.89 | SLC6A4 (0.53) | SLC6A4ADRA1AHTR1ASLC6A2ADRB2 | |
| SCHEMBL11153294 | 0.87 | ADRB2 (0.64) | SLC6A4ADRA1AHTR1ASLC6A2ADRB2 | |
| SCHEMBL11371503 | 0.84 | SLC6A4 (0.48) | SLC6A4ADRA1AHTR1ASLC6A2ADRB2 | |
| SCHEMBL11156039 | 0.84 | ADRB3 (0.67) | SLC6A4ADRA1AHTR1ASLC6A2ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005099699-A1 | COMBINATION OF (S)-AMLODIPINE AND A BETA-BLOCKER, AND METHODS FOR REDUCING HYPERTENSION | SEPRACOR INC. (US) | 2005-10-27 | — | — | WO | disclosed |