SCHEMBL111535

SCHEMBL111535

OC1=Cc2ccccc21

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28917152 0.90 KDM4E (0.40)
SCHEMBL9207972 0.85 GPR84 (0.42)
SCHEMBL9207977 0.85 GPR84 (0.42)
SCHEMBL12956160 0.79 MAPT (0.50)
SCHEMBL32665941 0.79
SCHEMBL9353957 0.78 CDC25B (0.52)
SCHEMBL5241115 0.74 MTNR1A (0.47)
SCHEMBL3805462 0.74 GPR84 (0.55)
SCHEMBL130420 0.72 KMT2A (0.59)
SCHEMBL10354666 0.69 ABCG2 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115340446-B Chiral benzocyclobutene alcohol, synthesis method and application thereof 复旦大学 2024-04-19 CN claimed
EP-1753713-B1 SYNTHESIS OF TETRACYCLINES AND ANALOGUES THEREOF HARVARD COLLEGE (US) 2016-07-27 EP claimed
CN-101027279-B Synthesis of tetracyclines and analogues thereof HARVARD COLLEGE 2013-03-27 CN claimed
EP-1753713-A4 SYNTHESIS OF TETRACYCLINES AND ANALOGUES THEREOF HARVARD COLLEGE (US) 2009-07-08 EP claimed
EP-2076133-A2 SYNTHESIS OF ENONE INTERMEDIATE The President and Fellows of Harvard College (US) 2009-07-08 EP claimed
WO-2008127361-A2 SYNTHESIS OF ENONE INTERMEDIATE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2008-10-23 WO claimed
CN-101027279-A Synthesis of tetracyclines and analogues thereof HARVARD COLLEGE (US) 2007-08-29 CN claimed
EP-1753713-A2 SYNTHESIS OF TETRACYCLINES AND ANALOGUES THEREOF The President and Fellows of Harvard College (US) 2007-02-21 EP claimed
WO-2005112945-A2 SYNTHESIS OF TETRACYCLINES AND ANALOGUES THEREOF THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2005-12-01 WO claimed
EP-0604575-A1 PROCESS FOR PREPARING HYDROXYBENZOCYCLOBUTENES THE DOW CHEMICAL COMPANY (US) 1994-07-06 EP claimed
EP-0564547-A1 PROCESS FOR THE PREPARATION OF ARYLCYCLOBUTENE TERMINATED CONDENSATION POLYMERS THE DOW CHEMICAL COMPANY (US) 1993-10-13 EP claimed
US-5227536-A PROCESS FOR PREPARING HYDROXYBENZOCYCLOBUTENES THE DOW CHEMICAL COMPANY (US) 1993-07-13 US claimed
WO-1993006072-A1 PROCESS FOR PREPARING HYDROXYBENZOCYCLOBUTENES THE DOW CHEMICAL COMPANY (US) 1993-04-01 WO claimed
US-5171824-A Polymerizing precursors of polycarbonate, polyester or polyestercarbonate compound along with multihydric compounds and benzocyclobutene derivatives THE DOW CHEMICAL COMPANY (US) 1992-12-15 US claimed
WO-1992011308-A1 PROCESS FOR THE PREPARATION OF ARYLCYCLOBUTENE TERMINATED CONDENSATION POLYMERS THE DOW CHEMICAL COMPANY (US) 1992-07-09 WO claimed
US-5120884-A Preparation of hydroxy arylcyclobutenes THE DOW CHEMICAL COMPANY (US) 1992-06-09 US claimed
EP-4686368-A1 A MOLECULAR SOLAR THERMAL SYSTEM (MOST) FOR LONG-TERM STORAGE OF SOLAR ENERGY Johannes Gutenberg-Universität Mainz (DE) 2026-01-28 EP disclosed
CN-115340446-B Chiral benzocyclobutene alcohol, synthesis method and application thereof 复旦大学 2024-04-19 CN disclosed
WO-1992011308-A1 PROCESS FOR THE PREPARATION OF ARYLCYCLOBUTENE TERMINATED CONDENSATION POLYMERS THE DOW CHEMICAL COMPANY (US) 1992-07-09 WO disclosed
US-5120884-A Preparation of hydroxy arylcyclobutenes THE DOW CHEMICAL COMPANY (US) 1992-06-09 US disclosed