Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | TDP2 | O95551 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | CDC25A | P30304 | 1/20 | 0.31 |
| ▸ | CDC25B | P30305 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL111535 | 0.90 | — | — | |
| SCHEMBL9207972 | 0.76 | GPR84 (0.42) | KDM4EMAPTALDH1A1HPGDCYP3A4 | |
| SCHEMBL9207977 | 0.76 | GPR84 (0.42) | KDM4EMAPTALDH1A1HPGDCYP3A4 | |
| SCHEMBL12956160 | 0.71 | MAPT (0.50) | KDM4EMAPTALDH1A1HPGDCYP3A4 | |
| SCHEMBL32665941 | 0.71 | — | — | |
| SCHEMBL9353957 | 0.70 | CDC25B (0.52) | KDM4EMAPTALDH1A1HPGDCYP3A4 | |
| SCHEMBL6924024 | 0.69 | MEN1 (0.47) | KDM4EMAPTALDH1A1HPGDCYP3A4 | |
| SCHEMBL5241115 | 0.67 | MTNR1A (0.47) | KDM4EMAPTALDH1A1HPGDCYP3A4 | |
| SCHEMBL3805462 | 0.67 | GPR84 (0.55) | KDM4EMAPTALDH1A1HPGDCYP3A4 | |
| SCHEMBL130420 | 0.65 | KMT2A (0.59) | KDM4EMAPTALDH1A1HPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115340446-B | Chiral benzocyclobutene alcohol, synthesis method and application thereof | 复旦大学 | 2024-04-19 | — | — | CN | disclosed |
| CN-115340446-A | Chiral benzocyclobutene alcohol, and synthesis method and application thereof | 复旦大学 | 2022-11-15 | — | — | CN | disclosed |