Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.44 |
| ▸ | TYRO3 | Q06418 | 5/20 | 0.40 |
| ▸ | MERTK | Q12866 | 5/20 | 0.40 |
| ▸ | FLT3 | P36888 | 4/20 | 0.40 |
| ▸ | GAS6 | Q14393 | 4/20 | 0.40 |
| ▸ | AXL | P30530 | 3/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.40 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.40 |
| ▸ | KCNH3 | Q9ULD8 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.37 |
| ▸ | BCL6 | P41182 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11399515 | 0.90 | GAA (0.41) | TYRO3MERTKFLT3GAS6AXL | |
| SCHEMBL10996367 | 0.85 | TLR8 (0.43) | TYRO3MERTKFLT3GAS6AXL | |
| SCHEMBL10998571 | 0.83 | KMT2A (0.43) | TYRO3MERTKFLT3GAS6AXL | |
| SCHEMBL11002056 | 0.83 | KMT2A (0.43) | TYRO3MERTKFLT3GAS6AXL | |
| SCHEMBL11240946 | 0.83 | SYK (0.35) | — | |
| SCHEMBL11236452 | 0.81 | KCNH3 (0.43) | TYRO3MERTKGAS6P2RX3P2RX2 | |
| SCHEMBL10998512 | 0.81 | MAPT (0.37) | TYRO3MERTKFLT3GAS6AXL | |
| SCHEMBL11244119 | 0.80 | CA1 (0.32) | — | |
| SCHEMBL11245946 | 0.79 | MERTK (0.32) | TYRO3MERTKFLT3GAS6AXL | |
| SCHEMBL11432081 | 0.79 | TSHR (0.43) | TYRO3MERTKFLT3GAS6CSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0035161-B1 | CEPHALOSPORINS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS | Dr. Karl Thomae GmbH (DE) | 1983-11-23 | — | — | EP | disclosed |
| US-4370327-A | Cephalosporins and pharmaceutical compositions | BOEHRINGER INGELHEIM GMBH (DE) | 1983-01-25 | — | — | US | disclosed |
| EP-0016374-B1 | PENICILLINS, THEIR SALTS, PROCESS FOR THEIR PREPARATION AND THERAPEUTIC AGENTS CONTAINING THESE COMPOUNDS | Dr. Karl Thomae GmbH (DE) | 1982-03-03 | — | — | EP | disclosed |
| US-4289775-A | BACTERICIDAL ANTIBIOTICS | KARL THOMAE GMBH (DE) | 1981-09-15 | — | — | US | disclosed |
| EP-0035161-A2 | Cephalosporins, processes for their preparation and pharmaceutical compositions containing these compounds | Dr. Karl Thomae GmbH (DE) | 1981-09-09 | — | — | EP | disclosed |
| EP-0016374-A1 | Penicillins, their salts, process for their preparation and therapeutic agents containing these compounds | Dr. Karl Thomae GmbH (DE) | 1980-10-01 | — | — | EP | disclosed |