Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.43 |
| ▸ | MERTK | Q12866 | 14/20 | 0.43 |
| ▸ | FLT3 | P36888 | 12/20 | 0.43 |
| ▸ | TYRO3 | Q06418 | 12/20 | 0.43 |
| ▸ | GAS6 | Q14393 | 12/20 | 0.43 |
| ▸ | AXL | P30530 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10998571 | 0.94 | KMT2A (0.43) | MERTKFLT3TYRO3GAS6AXL | |
| SCHEMBL11002056 | 0.94 | KMT2A (0.43) | MERTKFLT3TYRO3GAS6AXL | |
| SCHEMBL10998512 | 0.90 | MAPT (0.37) | MERTKFLT3TYRO3GAS6AXL | |
| SCHEMBL11266023 | 0.86 | MERTK (0.36) | MERTKFLT3TYRO3GAS6AXL | |
| SCHEMBL11154337 | 0.85 | NUDT1 (0.44) | MERTKFLT3TYRO3GAS6AXL | |
| SCHEMBL11432081 | 0.84 | TSHR (0.43) | MERTKFLT3TYRO3GAS6KDM4E | |
| SCHEMBL11236452 | 0.83 | KCNH3 (0.43) | TLR8MERTKTYRO3GAS6MAPT | |
| SCHEMBL11000318 | 0.83 | CYP1A2 (0.41) | KDM4EMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL11267279 | 0.82 | KCNH3 (0.33) | MERTKFLT3TYRO3GAS6AXL | |
| SCHEMBL11399515 | 0.81 | GAA (0.41) | MERTKFLT3TYRO3GAS6AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE31926-E | Penicillins and salts thereof | BOEHRINGER INGELHEIM GMBH (DE) | 1985-06-25 | — | — | US | disclosed |
| EP-0003814-B1 | PENICILLINS, THEIR SALTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1981-12-16 | — | — | EP | disclosed |
| US-4241056-A | ANTIBIOTICS | BOEHRINGER INGELHEIM GMBH (DE) | 1980-12-23 | — | — | US | disclosed |
| EP-0003814-A2 | Penicillins, their salts, process for their preparation and pharmaceutical compositions containing them | Dr. Karl Thomae GmbH (DE) | 1979-09-05 | — | — | EP | disclosed |