Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.32 |
| ▸ | CA2 | P00918 | 6/20 | 0.32 |
| ▸ | CA9 | Q16790 | 6/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11154337 | 0.80 | NUDT1 (0.44) | — | |
| SCHEMBL11240946 | 0.79 | SYK (0.35) | — | |
| SCHEMBL10996367 | 0.79 | TLR8 (0.43) | MEN1ALDH1A1MAPTMAPK1RAB9A | |
| SCHEMBL11399515 | 0.77 | GAA (0.41) | MEN1ALDH1A1GAAMAPK1KMT2A | |
| SCHEMBL10998571 | 0.77 | KMT2A (0.43) | KMT2A | |
| SCHEMBL11002056 | 0.77 | KMT2A (0.43) | KMT2A | |
| SCHEMBL11236452 | 0.75 | KCNH3 (0.43) | MAPT | |
| SCHEMBL11249857 | 0.75 | MRGPRX1 (0.38) | CA1CA2CA9CA12CA14 | |
| SCHEMBL10998512 | 0.75 | MAPT (0.37) | CA1CA2CA9MEN1ALDH1A1 | |
| SCHEMBL11391206 | 0.74 | KDM4E (0.36) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0016374-B1 | PENICILLINS, THEIR SALTS, PROCESS FOR THEIR PREPARATION AND THERAPEUTIC AGENTS CONTAINING THESE COMPOUNDS | Dr. Karl Thomae GmbH (DE) | 1982-03-03 | — | — | EP | disclosed |
| US-4289775-A | BACTERICIDAL ANTIBIOTICS | KARL THOMAE GMBH (DE) | 1981-09-15 | — | — | US | disclosed |
| EP-0016374-A1 | Penicillins, their salts, process for their preparation and therapeutic agents containing these compounds | Dr. Karl Thomae GmbH (DE) | 1980-10-01 | — | — | EP | disclosed |