Succinic Acid

SCHEMBL11154339

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nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRB1 CDK4 CDK6 CHRM2 CHRM3 DPP4 DRD2 DRD3 DRD4 EGFR HRH1 HTR1B HTR1D HTR1F HTR2A HTR2C HTR4 SLC6A2 SLC6A4

The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	LMNA	P02545	4/20	0.60

▸	EGLN1	Q9GZT9	3/20	0.60

▸	ALKBH5	Q6P6C2	1/20	0.60

▸	SUCNR1	Q9BXA5	1/20	0.60

▸	MAPK1	P28482	1/20	0.53

▸	SLC13A3	Q8WWT9	1/20	0.53

▸	OR51E2	Q9H255	1/20	0.53

▸	FFAR3	O14843	3/20	0.50

▸	HDAC3	O15379	3/20	0.50

▸	HDAC1	Q13547	3/20	0.50

▸	HDAC2	Q92769	3/20	0.50

▸	HDAC8	Q9BY41	3/20	0.50

▸	CA1	P00915	2/20	0.46

▸	SLC15A2	Q16348	1/20	0.45

▸	SLC22A6	Q4U2R8	1/20	0.44

▸	CA4	P22748	1/20	0.44

▸	CASP1	P29466	1/20	0.42

▸	TSHR	P16473	1/20	0.42

▸	NFKB1	P19838	1/20	0.42

▸	PMP22	Q01453	1/20	0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Succinic Acid SCHEMBL619046	1.00	LMNA (0.60)	LMNAEGLN1ALKBH5SUCNR1MAPK1
Succinic Acid SCHEMBL151456	1.00	LMNA (0.60)	LMNAEGLN1ALKBH5SUCNR1MAPK1
Succinic Acid SCHEMBL2029680	1.00	LMNA (0.60)	LMNAEGLN1ALKBH5SUCNR1MAPK1
Succinic Acid SCHEMBL104934	1.00	—	—
Succinic Acid SCHEMBL18839954	1.00	LMNA (0.60)	LMNAEGLN1ALKBH5SUCNR1MAPK1
Succinic Acid SCHEMBL155053	1.00	LMNA (0.60)	LMNAEGLN1ALKBH5SUCNR1MAPK1
Succinic Acid SCHEMBL7567030	0.97	LMNA (0.56)	LMNAEGLN1ALKBH5SUCNR1MAPK1
Succinic Acid SCHEMBL497058	0.97	LMNA (0.56)	LMNAEGLN1ALKBH5SUCNR1MAPK1
Succinic Acid SCHEMBL22656795	0.97	LMNA (0.56)	LMNAEGLN1ALKBH5SUCNR1MAPK1
Succinic Acid SCHEMBL31277093	0.97	LMNA (0.56)	LMNAEGLN1ALKBH5SUCNR1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-4416809-A	SULFO FATTY ACID ESTER SALT, FATTY ACID SOAP, AND POLYCARBOXYLIC ACID SALT	LION CORPORATION (JP)	1983-11-22	—	—	US	disclosed