Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.60 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.60 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.53 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.53 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL619046 | 1.00 | LMNA (0.60) | LMNAEGLN1ALKBH5SUCNR1MAPK1 | |
| Succinic Acid SCHEMBL11154339 | 1.00 | LMNA (0.60) | LMNAEGLN1ALKBH5SUCNR1MAPK1 | |
| Succinic Acid SCHEMBL151456 | 1.00 | LMNA (0.60) | LMNAEGLN1ALKBH5SUCNR1MAPK1 | |
| Succinic Acid SCHEMBL104934 | 1.00 | — | — | |
| Succinic Acid SCHEMBL18839954 | 1.00 | LMNA (0.60) | LMNAEGLN1ALKBH5SUCNR1MAPK1 | |
| Succinic Acid SCHEMBL155053 | 1.00 | LMNA (0.60) | LMNAEGLN1ALKBH5SUCNR1MAPK1 | |
| Succinic Acid SCHEMBL7567030 | 0.97 | LMNA (0.56) | LMNAEGLN1ALKBH5SUCNR1MAPK1 | |
| Succinic Acid SCHEMBL497058 | 0.97 | LMNA (0.56) | LMNAEGLN1ALKBH5SUCNR1MAPK1 | |
| Succinic Acid SCHEMBL22656795 | 0.97 | LMNA (0.56) | LMNAEGLN1ALKBH5SUCNR1MAPK1 | |
| Succinic Acid SCHEMBL31277093 | 0.97 | LMNA (0.56) | LMNAEGLN1ALKBH5SUCNR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119346163-A | Preparation method and application of rare earth-based copper molecular sieve denitration catalyst resistant to alkali metal poisoning | 包头稀土研究院 | 2025-01-24 | — | — | CN | claimed |
| CN-115732727-A | All-iron flow battery negative electrode electrolyte | 上海电气(安徽)储能科技有限公司 | 2023-03-03 | — | — | CN | claimed |
| EP-4110360-A1 | FORMULATION BASED ON NATURAL INGREDIENTS FOR USE IN TREATING PROCTOLOGICAL DISORDERS | Giuliani S.p.A. (IT) | 2023-01-04 | — | — | EP | claimed |
| EP-4642474-A1 | PLANT-MINERAL COMPOSITION BASED ON ALOE BARBADENSIS EXTRACT AND TRIMETHYLGLYCINE FOR PH-DEPENDENT REGULATION OF TYPE 3 AQUAPORINS AND TRANSEPIDERMAL WATER FLOW IN DEEP EPIDERMAL LAYERS | SkyLab AG (CH) | 2025-11-05 | — | — | EP | disclosed |
| CN-119346163-B | Preparation method and application of rare earth-based copper molecular sieve denitration catalyst resistant to alkali metal poisoning | 包头稀土研究院 | 2025-06-13 | — | — | CN | disclosed |
| CN-119346163-A | Preparation method and application of rare earth-based copper molecular sieve denitration catalyst resistant to alkali metal poisoning | 包头稀土研究院 | 2025-01-24 | — | — | CN | disclosed |
| US-12178900-B2 | Pharmaceutical compositions | JOYDERMA AG (CH) | 2024-12-31 | — | — | US | disclosed |
| WO-2024141322-A1 | PLANT-MINERAL COMPOSITION BASED ON ALOE BARBADENSIS EXTRACT AND TRIMETHYLGLYCINE FOR PH-DEPENDENT REGULATION OF TYPE 3 AQUAPORINS AND TRANSEPIDERMAL WATER FLOW IN DEEP EPIDERMAL LAYERS | SkyLab AG (CH) | 2024-07-04 | — | — | WO | disclosed |
| EP-4393470-A1 | PLANT-MINERAL COMPOSITION BASED ON ALOE BARBADENSIS EXTRACT AND TRIMETHYLGLYCINE FOR PH-DEPENDENT REGULATION OF TYPE 3 AQUAPORINS AND TRANSEPIDERMAL WATER FLOW IN DEEP EPIDERMAL LAYERS | SkyLab AG (CH) | 2024-07-03 | — | — | EP | disclosed |
| WO-2023190491-A1 | WATER-ABSORBING RESIN COMPOSITION, PRODUCTION METHOD THEREFOR, ABSORBER, AND ABSORBENT ARTICLE | 住友精化株式会社 | 2023-10-05 | — | — | WO | disclosed |
| CN-116195595-A | Activated hydrogen peroxide sanitizing compositions | 阿萨达有限责任公司 | 2023-06-02 | — | — | CN | disclosed |
| US-20100260759-A1 | IMMUNOSUPPRESSIVE POLYPEPTIDES AND NUCLEIC ACIDS | PERSEID THERAPEUTICS LLC (US) | 2010-10-14 | — | — | US | disclosed |
| US-7794718-B2 | Immunosuppressive polypeptides and nucleic acids | Perseid Therapeutics, LLC (US) | 2010-09-14 | — | — | US | disclosed |
| EP-2222697-A2 | IMMUNOSUPPRESSIVE POLYPEPTIDES AND NUCLEIC ACIDS | Perseid Therapeutics LLC (US) | 2010-09-01 | — | — | EP | disclosed |
| US-20090258031-A1 | IMMUNOSUPPRESSIVE POLYPEPTIDES AND NUCLEIC ACIDS | MAXYGEN, INC. (US) | 2009-10-15 | — | — | US | disclosed |
| WO-2009058564-A2 | IMMUNOSUPPRESSIVE POLYPEPTIDES AND NUCLEIC ACIDS | MAXYGEN, INC. (US) | 2009-05-07 | — | — | WO | disclosed |
| EP-0158964-B1 | TESTER FOR DETECTING A SUBSTANCE IN A BODY FLUID | TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION (JP) | 1990-11-14 | — | — | EP | disclosed |
| EP-0141244-B1 | TESTING AGENT FOR DETECTING A SUBTANCE IN A BODY FLUID | TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION (JP) | 1988-12-07 | — | — | EP | disclosed |
| EP-0158964-A2 | Tester for detecting a substance in a body fluid | TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION (JP) | 1985-10-23 | — | — | EP | disclosed |
| EP-0141244-A1 | Testing agent for detecting a subtance in a body fluid | TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION (JP) | 1985-05-15 | — | — | EP | disclosed |