Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | FAAH | O00519 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11152788 | 0.94 | MEN1 (0.34) | MEN1KMT2AALDH1A1FAAHMAPT | |
| SCHEMBL16842402 | 0.76 | HSD17B10 (0.35) | ALDH1A1MAPTLMNAKDM4EPOLB | |
| SCHEMBL11475333 | 0.74 | TDP1 (0.35) | ALDH1A1MAPTKDM4EPOLBTSHR | |
| SCHEMBL4441350 | 0.73 | MAPT (0.54) | ALDH1A1FAAHMAPTABCC4LMNA | |
| SCHEMBL9268587 | 0.71 | — | — | |
| SCHEMBL9974498 | 0.70 | KDM4E (0.34) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL2541730 | 0.70 | ALDH1A1 (0.38) | ALDH1A1MAPTLMNAKDM4EPOLB | |
| SCHEMBL515561 | 0.68 | TSHR (0.50) | KMT2AALDH1A1FAAHMAPTABCC4 | |
| SCHEMBL515402 | 0.68 | TSHR (0.56) | KMT2AALDH1A1FAAHMAPTABCC4 | |
| SCHEMBL11857611 | 0.67 | HDAC1 (0.45) | MAPTPOLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0008952-B1 | STEROID INTERMEDIATE, METHOD FOR PRODUCTION THEREOF AND METHOD OF PRODUCING ANOTHER STEROID INTERMEDIATE THEREFROM | Takeda Chemical Industries, Ltd. (JP) | 1983-04-13 | — | — | EP | disclosed |
| US-4267377-A | Intermediates for steroid synthesis | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-05-12 | — | — | US | disclosed |
| EP-0008952-A2 | Steroid intermediate, method for production thereof and method of producing another steroid intermediate therefrom | Takeda Chemical Industries, Ltd. (JP) | 1980-03-19 | — | — | EP | disclosed |