Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 6/20 | 0.45 |
| ▸ | CDK1 | P06493 | 3/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.45 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.45 |
| ▸ | CDK4 | P11802 | 8/20 | 0.45 |
| ▸ | CDK6 | Q00534 | 4/20 | 0.45 |
| ▸ | CCND1 | P24385 | 4/20 | 0.42 |
| ▸ | ACVR1 | Q04771 | 4/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.42 |
| ▸ | STK17A | Q9UEE5 | 2/20 | 0.42 |
| ▸ | PLK4 | O00444 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 2/20 | 0.41 |
| ▸ | CDK7 | P50613 | 2/20 | 0.41 |
| ▸ | CDK9 | P50750 | 2/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.41 |
| ▸ | WEE1 | P30291 | 2/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12727722 | 1.00 | CDK2 (0.45) | CDK2CDK1CCNB1CCNA2CCNA1 | |
| SCHEMBL2565742 | 0.92 | CDK4 (0.42) | CDK1CCNB1CDK4CDK6CCND1 | |
| SCHEMBL1115258 | 0.91 | CDK4 (0.51) | CDK2CDK1CCNB1CCNA2CCNA1 | |
| SCHEMBL12727721 | 0.91 | CDK4 (0.51) | CDK2CDK1CCNB1CCNA2CCNA1 | |
| SCHEMBL15875549 | 0.84 | CDK4 (0.47) | CDK2CDK1CCNB1CCNA2CCNA1 | |
| SCHEMBL12727736 | 0.83 | CDK4 (0.51) | CDK2CDK1CCNB1CCNA2CCNA1 | |
| SCHEMBL12727743 | 0.81 | CDK4 (0.49) | CDK2CDK1CCNB1CCNA2CCNA1 | |
| SCHEMBL12727726 | 0.80 | CDK4 (0.39) | CDK1CCNB1CDK4CDK6CCND1 | |
| SCHEMBL12162446 | 0.80 | JAK3 (0.40) | CDK2CDK1CCNB1CDK4CDK6 | |
| SCHEMBL1115176 | 0.80 | JAK3 (0.40) | CDK2CDK1CCNB1CDK4CDK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105801455-A | Method for oxidatively synthesizing p-carboxybenzene sulfonamide through oxygen | 中国矿业大学 | 2016-07-27 | — | — | CN | claimed |
| CN-103834432-B | A kind of method of ionic liquid intermediate fuel oil extraction oxidation sweetening | INSTITUTE OF COAL CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2016-01-27 | — | — | CN | claimed |
| CN-104557640-A | Method for preparing 2-nitro-4-methylsulfuryl benzoic acid by molecular oxygen catalytic oxidation | WUHAN CHEMAX CHEMICAL IND CO LTD | 2015-04-29 | — | — | CN | claimed |
| CN-103834432-A | Method for extracting, oxidizing and desulfuring fuel oil in ionic liquid | SHANXI COAL CHEM INST | 2014-06-04 | — | — | CN | claimed |
| CN-102391167-B | Method for preparing tert-butyl hydrogen peroxide and tert-butyl alcohol by oxidating isobutane | UNIV XIANGTAN | 2013-11-27 | — | — | CN | claimed |
| EP-2448889-B1 | PROCESS FOR THE PREPARATION OF PHENOL AND CYCLOHEXANONE | VERSALIS SPA (IT) | 2013-06-05 | — | — | EP | claimed |
| US-8389533-B2 | Gem-disubstituted and spirocyclic amino pyridines/pyrimidines as cell cycle inhibitors | AMGEN INC. (US) | 2013-03-05 | — | — | US | claimed |
| CN-102391167-A | Method for preparing tert-butyl hydrogen peroxide and tert-butyl alcohol by oxidating isobutane | UNIV XIANGTAN | 2012-03-28 | — | — | CN | claimed |
| EP-2278973-B1 | GEM-DISUBSTITUTED AND SPIROCYCLIC AMINO PYRIDINES/PYRIMIDINES AS CELL CYCLE INHIBITORS | AMGEN INC (US) | 2011-11-02 | — | — | EP | claimed |
| US-20110097305-A1 | Gem-Disubstituted and Spirocyclic Amino Pyridines/Pyrimidines as Cell Cycle Inhibitors | AMGEN INC. (US) | 2011-04-28 | — | — | US | claimed |
| US-20110098509-A1 | PROCESS FOR THE PREPARATION OF PHENOL BY MEANS OF NEW CATALYTIC SYSTEMS | POLIMERI EUROPA S.P.A. (IT) | 2011-04-28 | — | — | US | claimed |
| EP-2278973-A1 | GEM-DISUBSTITUTED AND SPIROCYCLIC AMINO PYRIDINES/PYRIMIDINES AS CELL CYCLE INHIBITORS | Amgen Inc. (US) | 2011-02-02 | — | — | EP | claimed |
| EP-1966114-B1 | SELECTIVE OXIDATION OF ALKYLBENZENES | EXXONMOBIL CHEM PATENTS INC (US) | 2010-11-17 | — | — | EP | claimed |
| WO-2009126584-A1 | GEM-DISUBSTITUTED AND SPIROCYCLIC AMINO PYRIDINES/PYRIMIDINES AS CELL CYCLE INHIBITORS | AMGEN INC. (US) | 2009-10-15 | — | — | WO | claimed |
| CN-101541745-A | Method for preparing phenol by using novel catalytic system | POLIMERI EUROPA SPA (IT) | 2009-09-23 | — | — | CN | claimed |
| EP-2069298-A1 | PROCESS FOR THE PREPARATION OF PHENOL BY MEANS OF NEW CATALYTIC SYSTEMS | Polimeri Europa S.p.A. (IT) | 2009-06-17 | — | — | EP | claimed |
| WO-2008037435-A1 | PROCESS FOR THE PREPARATION OF PHENOL BY MEANS OF NEW CATALYTIC SYSTEMS | POLIMERI EUROPA S.P.A. (IT) | 2008-04-03 | — | — | WO | claimed |
| CN-105801455-A | Method for oxidatively synthesizing p-carboxybenzene sulfonamide through oxygen | 中国矿业大学 | 2016-07-27 | — | — | CN | disclosed |
| CN-101048378-A | Process for the synthesis of n-alkoxyamines | CIBA SC HOLDING AG (CH) | 2007-10-03 | — | — | CN | disclosed |
| CN-1547564-A | Method for producing saturated alcohols, ketones, aldehydes and carboxylic acids | 1 | 2004-11-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098509-A1 | PROCESS FOR THE PREPARATION OF PHENOL BY MEANS OF NEW CATALYTIC SYSTEMS | HPD, AOX1, CYP2E1 | CDK2 1434/4885CDK1 1692/4885CCNB1 1587/4885 |
| US-20110097305-A1 | Gem-Disubstituted and Spirocyclic Amino Pyridines/Pyrimidines as Cell Cycle Inhibitors | CDK4, CDK3, CDK6 | CDK2 4/4885CDK1 22/4885CCNB1 25/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.