Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | HSPB1 | P04792 | 3/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MYOC | Q99972 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL275261 | 0.81 | PDE7A (0.51) | PDE7AALDH1A1MAPTHSPB1ATM | |
| SCHEMBL11155758 | 0.80 | ATM (0.53) | PDE7AALDH1A1MAPTHSPB1ATM | |
| SCHEMBL11159594 | 0.79 | PDE7A (0.51) | PDE7AALDH1A1MAPTHSPB1ATM | |
| SCHEMBL8964117 | 0.77 | ALDH1A1 (0.71) | ALDH1A1MAPTHSPB1MEN1KMT2A | |
| SCHEMBL11152402 | 0.76 | KMT2A (0.47) | PDE7AALDH1A1MAPTATMMEN1 | |
| SCHEMBL11152400 | 0.76 | KMT2A (0.47) | PDE7AALDH1A1MAPTATMMEN1 | |
| SCHEMBL31447962 | 0.74 | HSPB1 (0.53) | PDE7AALDH1A1MAPTHSPB1ATM | |
| SCHEMBL6918825 | 0.74 | HSPB1 (0.53) | PDE7AALDH1A1MAPTHSPB1ATM | |
| SCHEMBL11577394 | 0.72 | HSPB1 (0.68) | PDE7AALDH1A1MAPTHSPB1MEN1 | |
| SCHEMBL14451771 | 0.72 | TLR9 (0.61) | ALDH1A1MAPTHSPB1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4389416-A | DIURETICS | ABBOTT LABORATORIES (US) | 1983-06-21 | — | — | US | disclosed |