Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.71 |
| ▸ | MAPT | P10636 | 6/20 | 0.71 |
| ▸ | LMNA | P02545 | 6/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | HSPB1 | P04792 | 3/20 | 0.53 |
| ▸ | TLR4 | O00206 | 1/20 | 0.53 |
| ▸ | TLR2 | O60603 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15694955 | 0.86 | MAPT (0.54) | ALDH1A1MAPTLMNAKMT2AGAA | |
| SCHEMBL7632959 | 0.84 | HSPB1 (0.66) | ALDH1A1MAPTLMNAKMT2AHSPB1 | |
| SCHEMBL31599176 | 0.84 | LMNA (0.88) | ALDH1A1MAPTLMNAKMT2AGAA | |
| SCHEMBL7822262 | 0.83 | LMNA (0.58) | ALDH1A1MAPTLMNAKMT2AGAA | |
| SCHEMBL15864061 | 0.83 | ALDH1A1 (1.00) | ALDH1A1MAPTLMNAKMT2AMEN1 | |
| SCHEMBL6928480 | 0.81 | MAPT (0.56) | ALDH1A1MAPTLMNAKMT2AGAA | |
| SCHEMBL8964120 | 0.81 | LMNA (0.56) | ALDH1A1MAPTLMNAKMT2AGAA | |
| SCHEMBL8964023 | 0.80 | ALDH1A1 (0.54) | ALDH1A1MAPTLMNAKMT2ACYP1A2 | |
| SCHEMBL9087468 | 0.80 | HSPB1 (0.59) | ALDH1A1MAPTLMNAKMT2AHSPB1 | |
| SCHEMBL31241187 | 0.79 | LMNA (0.92) | ALDH1A1LMNAKMT2AGAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240116039-A1 | RUTHENIUM-BASED METATHESIS CATALYSTS, PRECURSORS FOR THEIR PREPARATION AND THEIR USE | UMICORE AG & CO. KG (DE) | 2024-04-11 | — | — | US | disclosed |
| US-11918985-B2 | Ruthenium-based metathesis catalysts, precursors for their preparation and their use | UMICORE AG & CO. KG (DE) | 2024-03-05 | — | — | US | disclosed |
| US-20230149911-A1 | RUTHENIUM-BASED METATHESIS CATALYSTS, PRECURSORS FOR THEIR PREPARATION AND THEIR USE | UMICORE AG & CO. KG (DE) | 2023-05-18 | — | — | US | disclosed |
| US-11577232-B2 | Ruthenium-based metathesis catalysts, precursors for their preparation and their use | UMICORE AG & CO. KG (DE) | 2023-02-14 | — | — | US | disclosed |
| US-20220118434-A1 | RUTHENIUM-BASED METATHESIS CATALYSTS, PRECURSORS FOR THEIR PREPARATION AND THEIR USE | UMICORE AG & CO. KG (DE) | 2022-04-21 | — | — | US | disclosed |
| US-11241680-B2 | Ruthenium-based metathesis catalysts, precursors for their preparation and their use | UMICORE AG & CO. KG | 2022-02-08 | — | — | US | disclosed |
| US-20180297019-A1 | RUTHENIUM-BASED METATHESIS CATALYSTS, PRECURSORS FOR THEIR PREPARATION AND THEIR USE | UMICORE AG & CO KG (DE) | 2018-10-18 | — | — | US | disclosed |
| CN-104768961-B | Ruthenium base metathesis catalyst, for its preparation precursor with and application thereof | 优美科股份公司及两合公司 | 2017-11-24 | — | — | CN | disclosed |
| EP-2912048-B1 | RUTHENIUM-BASED METATHESIS CATALYSTS, PRECURSORS FOR THEIR PREPARATION AND THEIR USE | UMICORE AG & CO KG (DE) | 2017-07-19 | — | — | EP | disclosed |
| US-20150266009-A1 | RUTHENIUM-BASED METATHESIS CATALYSTS, PRECURSORS FOR THEIR PREPARATION AND THEIR USE | UMICORE AG & CO KG (DE) | 2015-09-24 | — | — | US | disclosed |
| EP-2912048-A1 | RUTHENIUM-BASED METATHESIS CATALYSTS, PRECURSORS FOR THEIR PREPARATION AND THEIR USE | Umicore AG & Co. KG (DE) | 2015-09-02 | — | — | EP | disclosed |
| CN-104768961-A | Ruthenium-based metathesis catalysts, precursors for their preparation and their use | UMICORE AG & CO KG | 2015-07-08 | — | — | CN | disclosed |
| WO-2014067767-A1 | RUTHENIUM-BASED METATHESIS CATALYSTS, PRECURSORS FOR THEIR PREPARATION AND THEIR USE | UMICORE AG & CO. KG (DE) | 2014-05-08 | — | — | WO | disclosed |
| EP-2725030-A1 | Ruthenium-based metathesis catalysts, precursors for their preparation and their use | Umicore AG & Co. KG (DE) | 2014-04-30 | — | — | EP | disclosed |
| CN-101429132-A | Synthesis of 1,3-di(4-aminophenoxy)benzene | SHANGHAI GUCHUANG NEW CHEMICAL (CN) | 2009-05-13 | — | — | CN | disclosed |
| US-5525614-A | TREATING VASCULAR RESTENOSIS, CNS DISORDERS | WARNER-LAMBERT COMPANY (US) | 1996-06-11 | — | — | US | disclosed |
| US-5489686-A | CARDIOVASCULAR DISORDER, NERVOUS SYSTEM DISORDER, ANTIDIURETIC , PSYCHLOGICAL DISORDER, ANTIDEPRESSANTS | WARNER-LAMBERT COMPANY (US) | 1996-02-06 | — | — | US | disclosed |
| EP-0641326-A1 | SUBSTITUTED 1,2,3,4-TETRAHYDROISOQUINOLINES WITH ANGIOTENSIN II RECEPTOR ANTAGONIST PROPERTIES | WARNER-LAMBERT COMPANY (US) | 1995-03-08 | — | — | EP | disclosed |
| US-5350757-A | Treatment of vascular restenosis, nervous system disorders and cognition enhancement | WARNER-LAMBERT COMPANY (US) | 1994-09-27 | — | — | US | disclosed |
| WO-1993023378-A1 | SUBSTITUTED 1,2,3,4-TETRAHYDROISOQUINOLINES WITH ANGIOTENSIN II RECEPTOR ANTAGONIST PROPERTIES | WARNER-LAMBERT COMPANY (US) | 1993-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11241680-B2 | Ruthenium-based metathesis catalysts, precursors for their preparation and their use | HMBS, RRP12, RNF168 | ALDH1A1 844/4885MAPT 1360/4885LMNA 4812/4885 |
| US-20230149911-A1 | RUTHENIUM-BASED METATHESIS CATALYSTS, PRECURSORS FOR THEIR PREPARATION AND THEIR USE | HMBS, RRP12, RNF168 | ALDH1A1 844/4885MAPT 1360/4885LMNA 4812/4885 |
| US-11577232-B2 | Ruthenium-based metathesis catalysts, precursors for their preparation and their use | HMBS, RRP12, RNF168 | ALDH1A1 844/4885MAPT 1360/4885LMNA 4812/4885 |
| US-20240116039-A1 | RUTHENIUM-BASED METATHESIS CATALYSTS, PRECURSORS FOR THEIR PREPARATION AND THEIR USE | HMBS, RRP12, RNF168 | ALDH1A1 844/4885MAPT 1360/4885LMNA 4812/4885 |
| US-20220118434-A1 | RUTHENIUM-BASED METATHESIS CATALYSTS, PRECURSORS FOR THEIR PREPARATION AND THEIR USE | HMBS, RRP12, RNF168 | ALDH1A1 844/4885MAPT 1360/4885LMNA 4812/4885 |
| US-11918985-B2 | Ruthenium-based metathesis catalysts, precursors for their preparation and their use | HMBS, RRP12, RNF168 | ALDH1A1 844/4885MAPT 1360/4885LMNA 4812/4885 |
| US-20180297019-A1 | RUTHENIUM-BASED METATHESIS CATALYSTS, PRECURSORS FOR THEIR PREPARATION AND THEIR USE | HMBS, RRP12, RNF168 | ALDH1A1 844/4885MAPT 1360/4885LMNA 4812/4885 |
| US-20150266009-A1 | RUTHENIUM-BASED METATHESIS CATALYSTS, PRECURSORS FOR THEIR PREPARATION AND THEIR USE | HMBS, RRP12, RNF168 | ALDH1A1 844/4885MAPT 1360/4885LMNA 4812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.