Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | IAPP | P10997 | 2/20 | 0.46 |
| ▸ | ELANE | P08246 | 4/20 | 0.44 |
| ▸ | CTSG | P08311 | 4/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 2/20 | 0.43 |
| ▸ | BID | P55957 | 3/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.42 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.42 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.42 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.42 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27765350 | 0.88 | GABRA1 (0.46) | ALOX5PTGS2IAPPELANECTSG | |
| SCHEMBL201764 | 0.86 | ALOX5 (0.61) | ALOX5PTGS2IAPPELANECTSG | |
| Hydrogen Sulfide SCHEMBL28293295 | 0.84 | ALOX5 (0.59) | ALOX5PTGS2IAPPELANECTSG | |
| SCHEMBL1024684 | 0.82 | ALOX5 (0.58) | ALOX5PTGS2IAPPELANECTSG | |
| SCHEMBL1023094 | 0.80 | GABRA1 (0.71) | ALOX5PTGS2IAPPELANECTSG | |
| SCHEMBL10475391 | 0.80 | ALOX5 (0.56) | ALOX5PTGS2IAPPELANECTSG | |
| SCHEMBL21286977 | 0.80 | LIPG (0.40) | ALOX5PTGS2TYRBIDMCL1 | |
| SCHEMBL2467818 | 0.80 | ALOX5 (0.56) | ALOX5PTGS2IAPPELANECTSG | |
| SCHEMBL8448603 | 0.80 | ALOX5 (0.66) | ALOX5PTGS2ELANECTSGGABRA1 | |
| SCHEMBL27985283 | 0.80 | ALOX5 (0.66) | ALOX5PTGS2ELANECTSGGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440515-A | Substituted benzofuranyl and benzoxazole based compound and application thereof | 卡尔约药物治疗公司 | 2018-08-24 | — | — | CN | disclosed |
| EP-3163332-A1 | RESIN COMPOSITION FOR REFLECTIVE MATERIAL, AND REFLECTIVE PANEL INCLUDING SAME | Mitsui Chemicals, Inc. (JP) | 2017-05-03 | — | — | EP | disclosed |
| WO-1983000333-A1 | ANTI-HYPERTENSOR, HETEROCYCLICALLY DI-ORTHOSUBSTITUTED PHENOLS | TEULON, JEAN-MARIE | 1983-02-03 | — | — | WO | disclosed |
| EP-0070779-A2 | Di-ortho-substituted phenols of which one of the substitutions is a heterocycle, process for their preparation, anti-hypertensive medicines containing them and synthesis intermediates | CARPIBEM (CENTRE D'ACTIVITE ET DE RECHERCHE PHARMACEUTIQUE INDUSTRIELLE BIOLOGIQUE ET MEDICALE) Société Anonyme dite: (FR) | 1983-01-26 | — | — | EP | disclosed |