SCHEMBL11157208

SCHEMBL11157208

CC(=O)c1c(N)c(CC2CO2)c(CC2CO2)c(-c2ccc(N)cc2)c1C(C)=O

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11155307 0.83 KMT2A (0.38)
Methylamine SCHEMBL29171068 0.82 ALDH1A1 (0.32) MAOA
SCHEMBL9857428 0.80 ALDH1A1 (0.33)
Methane SCHEMBL2463091 0.79 ALDH1A1 (0.32)
SCHEMBL11157202 0.70 THRB (0.34)
SCHEMBL821135 0.69 MAOA (0.38) MAOA
SCHEMBL16752034 0.68 MEN1 (0.44)
SCHEMBL28317497 0.68 MAOA (0.30) MAOA
SCHEMBL28347832 0.67 TDP1 (0.36)
SCHEMBL16752037 0.67 MEN1 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4421897-A ADHESIVES, COATINGS, MOLDING MATERIALS CIBA-GEIGY CORPORATION (US) 1983-12-20 US disclosed
EP-0018950-B1 CRYSTALLINE EPOXY RESIN BASED ONE COMPONENT SYSTEMS AND THEIR APPLICATION CIBA-GEIGY AG (CH) 1983-07-13 EP disclosed
US-4339571-A DIGLYCIDYL ISOPHTHALATE, OR TEREPHTHALATE CIBA-GEIGY CORPORATION (US) 1982-07-13 US disclosed
EP-0018950-A1 Crystalline epoxy resin based one component systems and their application CIBA-GEIGY AG (CH) 1980-11-12 EP disclosed