Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 5/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11864357 | 0.86 | MAPT (0.57) | LMNATP53MAPT | |
| SCHEMBL11862644 | 0.83 | KMT2A (0.54) | LMNAMAPTMEN1KMT2APOLB | |
| SCHEMBL11460792 | 0.78 | CASR (0.62) | CASRLMNATP53MAPT | |
| SCHEMBL11160051 | 0.78 | CASR (0.59) | CASRLMNATP53MAPT | |
| SCHEMBL11462576 | 0.78 | CASR (0.59) | CASRLMNATP53MAPTKMT2A | |
| SCHEMBL11602843 | 0.78 | CASR (0.68) | CASRLMNAMAPTMEN1KMT2A | |
| Ciproquazone SCHEMBL287449 | 0.78 | CASR (0.58) | CASRLMNATP53MAPT | |
| SCHEMBL11164228 | 0.77 | CASR (0.57) | CASRLMNATP53MAPTKMT2A | |
| SCHEMBL11158937 | 0.77 | CASR (0.57) | CASRLMNATP53MAPT | |
| SCHEMBL11741121 | 0.75 | ALDH1A1 (0.41) | LMNATP53MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4387223-A | Process for preparing 2(1H)-quinazolinone derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-06-07 | — | — | US | disclosed |