Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | F2RL3 | Q96RI0 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | F2R | P25116 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11160245 | 0.86 | L3MBTL1 (0.55) | KMT2AMEN1L3MBTL1POLBALDH1A1 | |
| SCHEMBL11167732 | 0.84 | MAPT (0.61) | KMT2AMEN1L3MBTL1POLBALDH1A1 | |
| SCHEMBL11864357 | 0.84 | MAPT (0.57) | MAPTLMNA | |
| SCHEMBL11861596 | 0.83 | L3MBTL1 (0.59) | KMT2AMEN1L3MBTL1POLBALDH1A1 | |
| SCHEMBL11157565 | 0.83 | CASR (0.55) | KMT2AMEN1POLBMAPTLMNA | |
| SCHEMBL11160397 | 0.82 | L3MBTL1 (0.57) | KMT2AMEN1L3MBTL1POLBALDH1A1 | |
| SCHEMBL11604828 | 0.82 | KMT2A (0.60) | KMT2AMEN1L3MBTL1POLBALDH1A1 | |
| SCHEMBL11638539 | 0.82 | L3MBTL1 (0.57) | KMT2AMEN1L3MBTL1POLBALDH1A1 | |
| SCHEMBL11634947 | 0.80 | MAPT (0.56) | KMT2AMEN1L3MBTL1POLBF2RL3 | |
| SCHEMBL11873847 | 0.80 | ALDH1A1 (0.39) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3953446-A | Process for preparing quinazolines | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-04-27 | — | — | US | disclosed |