Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | CASP9 | P55211 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11157586 | 0.84 | MAPT (0.47) | ALDH1A1NPSR1HPGDKDM4EHSD17B10 | |
| SCHEMBL11148380 | 0.83 | EGFR (0.40) | ALDH1A1NPSR1KDM4EKMT2AMEN1 | |
| SCHEMBL11157607 | 0.81 | THRA (0.49) | ALDH1A1NPSR1HPGDKDM4EHSD17B10 | |
| SCHEMBL11150315 | 0.81 | ALDH1A1 (0.45) | ALDH1A1NPSR1HPGDKDM4EHSD17B10 | |
| SCHEMBL11150311 | 0.81 | CYP4F2 (0.44) | ALDH1A1HPGDKDM4EHSD17B10KMT2A | |
| SCHEMBL11148393 | 0.81 | ALDH1A1 (0.49) | ALDH1A1NPSR1HPGDKDM4EHSD17B10 | |
| SCHEMBL11141660 | 0.81 | HPGD (0.52) | ALDH1A1NPSR1HPGDKDM4EHSD17B10 | |
| SCHEMBL11159558 | 0.80 | ALDH1A1 (0.48) | ALDH1A1NPSR1HPGDKDM4EHSD17B10 | |
| SCHEMBL434786 | 0.79 | GAA (0.68) | ALDH1A1NPSR1HPGDKDM4EHSD17B10 | |
| SCHEMBL10818963 | 0.77 | ALDH1A1 (0.56) | ALDH1A1NPSR1HPGDKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4389416-A | DIURETICS | ABBOTT LABORATORIES (US) | 1983-06-21 | — | — | US | disclosed |