Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 7/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.48 |
| ▸ | CXCR1 | P25024 | 4/20 | 0.48 |
| ▸ | CXCR2 | P25025 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.48 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2890863 | 0.83 | PTGS1 (0.54) | PTGS1PTGS2CXCR1CXCR2SMN1; SMN2 | |
| SCHEMBL9622822 | 0.81 | CYP1A2 (0.45) | SMN1; SMN2LMNAALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL11502156 | 0.80 | CA1 (0.40) | SMN1; SMN2CYP1A2CYP2D6PKMNPSR1 | |
| SCHEMBL27640013 | 0.80 | PTGS2 (0.54) | PTGS1PTGS2CXCR1CXCR2SMN1; SMN2 | |
| SCHEMBL9677464 | 0.79 | LMNA (0.48) | LMNAALDH1A1MAPK1POLB | |
| SCHEMBL15295485 | 0.78 | TAAR1 (0.53) | PTGS1PTGS2CXCR1CXCR2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4143443 | 0.78 | PTGS2 (0.53) | PTGS1PTGS2CXCR1CXCR2SMN1; SMN2 | |
| SCHEMBL15295486 | 0.78 | TAAR1 (0.53) | PTGS1PTGS2CXCR1CXCR2SMN1; SMN2 | |
| SCHEMBL4264095 | 0.78 | TAAR1 (0.53) | PTGS1PTGS2CXCR1CXCR2SMN1; SMN2 | |
| SCHEMBL9425565 | 0.78 | PTGS2 (0.56) | PTGS1PTGS2CXCR1CXCR2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0094586-A2 | Glycerol derivatives, process for preparing same and pharmaceutical composition containing same | ONO PHARMACEUTICAL CO., LTD. (JP) | 1983-11-23 | — | — | EP | disclosed |