Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 12/20 | 0.74 |
| ▸ | ADRA2B | P18089 | 10/20 | 0.74 |
| ▸ | ADRA1A | P35348 | 17/20 | 0.60 |
| ▸ | ADRA1D | P25100 | 14/20 | 0.59 |
| ▸ | ADRA1B | P35368 | 13/20 | 0.59 |
| ▸ | ADRA2A | P08913 | 11/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9654925 | 0.99 | ADRA2C (0.72) | ADRA2CADRA2BADRA1AADRA1DADRA1B | |
| SCHEMBL4209729 | 0.86 | ADRA2C (0.78) | ADRA2CADRA2BADRA1AADRA1DADRA1B | |
| SCHEMBL10965109 | 0.86 | ADRA2C (0.78) | ADRA2CADRA2BADRA1AADRA1DADRA1B | |
| Hydrochloric Acid SCHEMBL9654151 | 0.84 | ADRA2C (0.76) | ADRA2CADRA2BADRA1AADRA1DADRA1B | |
| Hydrochloric Acid SCHEMBL9654962 | 0.84 | ADRA2C (0.76) | ADRA2CADRA2BADRA1AADRA1DADRA1B | |
| SCHEMBL10965126 | 0.83 | ADRA2C (0.74) | ADRA2CADRA2BADRA1AADRA1DADRA1B | |
| Hydrochloric Acid SCHEMBL9654125 | 0.82 | ADRA2C (0.72) | ADRA2CADRA2BADRA1AADRA1DADRA1B | |
| Hydrochloric Acid SCHEMBL9654010 | 0.81 | ADRA2C (0.71) | ADRA2CADRA2BADRA1AADRA1DADRA1B | |
| SCHEMBL6366434 | 0.81 | ADRA2B (0.79) | ADRA2CADRA2BADRA1AADRA1DADRA1B | |
| Hydrochloric Acid SCHEMBL11163058 | 0.80 | ADRA2C (0.69) | ADRA2CADRA2BADRA1AADRA1DADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4414223-A | MITICIDWS | BURROUGHS WELLCOME CO. (US) | 1983-11-08 | — | — | US | claimed |
| US-4414223-A | MITICIDWS | BURROUGHS WELLCOME CO. (US) | 1983-11-08 | — | — | US | disclosed |