Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 11/20 | 0.78 |
| ▸ | ADRA2B | P18089 | 10/20 | 0.78 |
| ▸ | ADRA1A | P35348 | 14/20 | 0.58 |
| ▸ | ADRA1D | P25100 | 12/20 | 0.58 |
| ▸ | ADRA1B | P35368 | 11/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 9/20 | 0.58 |
| ▸ | MAOA | P21397 | 2/20 | 0.58 |
| ▸ | MAOB | P27338 | 2/20 | 0.58 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9654151 | 0.99 | ADRA2C (0.76) | ADRA2CADRA2BADRA1AADRA1DADRA1B | |
| SCHEMBL11231308 | 0.88 | ADRA2C (1.00) | ADRA2CADRA2BADRA1AADRA1DADRA1B | |
| Hydrochloric Acid SCHEMBL11227435 | 0.87 | ADRA2C (0.97) | ADRA2CADRA2BADRA1AADRA1DADRA1B | |
| SCHEMBL10965126 | 0.86 | ADRA2C (0.74) | ADRA2CADRA2BADRA1AADRA1DADRA1B | |
| SCHEMBL11157947 | 0.86 | ADRA2C (0.74) | ADRA2CADRA2BADRA1AADRA1DADRA1B | |
| Hydrochloric Acid SCHEMBL9654925 | 0.85 | ADRA2C (0.72) | ADRA2CADRA2BADRA1AADRA1DADRA1B | |
| Hydrochloric Acid SCHEMBL9654125 | 0.85 | ADRA2C (0.72) | ADRA2CADRA2BADRA1AADRA1DADRA1B | |
| Hydrochloric Acid SCHEMBL9654750 | 0.85 | ADRA2C (0.72) | ADRA2CADRA2BADRA1AADRA1DADRA1B | |
| SCHEMBL6366752 | 0.83 | ADRA2B (0.79) | ADRA2CADRA2BADRA1AADRA1DADRA1B | |
| Hydrochloric Acid SCHEMBL10448213 | 0.81 | ADRA2C (0.60) | ADRA2CADRA2BADRA1AADRA1DADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0058635-B1 | SUBSTITUTED 2-ANILINOMETHYL-2 IMIDAZOLIN DERIVATIVES, PROCESS FOR THEIR PREPARATION, AGENTS CONTAINING THEM AND THEIR PESTICIDAL APPLICATION | CIBA-GEIGY AG (CH) | 1985-07-03 | — | — | EP | claimed |
| US-20090209422-A1 | Insecticidal Substituted Aminoalkyl Heterocyclic and Heteroaryl Derivatives | BAYER CROPSCIENCE AG (DE) | 2009-08-20 | — | — | US | disclosed |
| US-20090209422-A1 | Insecticidal Substituted Aminoalkyl Heterocyclic and Heteroaryl Derivatives | BAYER CROPSCIENCE AG (DE) | 2009-08-20 | — | — | US | disclosed |
| US-20090209422-A1 | Insecticidal Substituted Aminoalkyl Heterocyclic and Heteroaryl Derivatives | BAYER CROPSCIENCE AG (DE) | 2009-08-20 | — | — | US | disclosed |
| EP-1879455-A1 | INSECTICIDAL SUBSTITUTED AMINOALKYL HETEROCYCLIC AND HETEROARYL DERIVATIVES | Bayer CropScience AG (DE) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006119411-A1 | INSECTICIDAL SUBSTITUTED AMINOALKYL HETEROCYCLIC AND HETEROARYL DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2006-11-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209422-A1 | Insecticidal Substituted Aminoalkyl Heterocyclic and Heteroaryl Derivatives | DDT, AADAC, DDC | ADRA2C 512/4885ADRA2B 728/4885ADRA1A 799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.