Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11145581 | 0.84 | MEN1 (0.52) | DYRK1AKMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL11149542 | 0.68 | PARP14 (0.47) | DYRK1AKMT2AMEN1L3MBTL1SMN1; SMN2 | |
| SCHEMBL11144388 | 0.67 | MEN1 (0.40) | DYRK1AKMT2AMEN1L3MBTL1TP53 | |
| SCHEMBL1690197 | 0.62 | MEN1 (0.48) | DYRK1AKMT2AMEN1KDM4EHSD17B10 | |
| SCHEMBL3123994 | 0.61 | BCL2L1 (0.47) | SMN1; SMN2KDM4EHSD17B10MAPTLMNA | |
| SCHEMBL11146665 | 0.61 | MAPT (0.38) | SMN1; SMN2TP53KDM4EHSD17B10MAPT | |
| SCHEMBL12412960 | 0.60 | MCL1 (0.38) | SMN1; SMN2TP53KDM4EHSD17B10MAPT | |
| SCHEMBL12412980 | 0.60 | MCL1 (0.38) | KMT2ASMN1; SMN2TP53KDM4EHSD17B10 | |
| SCHEMBL18252668 | 0.60 | BCL2L1 (0.46) | SMN1; SMN2KDM4EMAPTLMNAALDH1A1 | |
| SCHEMBL15497379 | 0.60 | BCL2L1 (0.46) | SMN1; SMN2KDM4EMAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0005357-B1 | N-(BENZOTHIENOPYRAZOL)-AMIDES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-02-09 | — | — | EP | disclosed |
| EP-0005357-A1 | N-(Benzothienopyrazol)-amides and pharmaceutical compositions containing them | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-11-14 | — | — | EP | disclosed |
| US-4140785-A | N-(benzothienopyrazol)amide antirhinoviral agents | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-02-20 | — | — | US | disclosed |