Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11216887 | 0.86 | ALDH1A1 (0.48) | TP53PKMMEN1KMT2AADORA1 | |
| SCHEMBL11149916 | 0.86 | TP53 (0.39) | PARP14TP53MEN1KMT2AKDM4E | |
| SCHEMBL11153753 | 0.86 | MAPT (0.43) | TP53PKMMEN1KMT2AKDM4E | |
| SCHEMBL11145581 | 0.83 | MEN1 (0.52) | PKMMEN1KMT2ADYRK1AKDM4E | |
| SCHEMBL11155492 | 0.83 | TP53 (0.41) | TP53MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL11147960 | 0.83 | ALDH1A1 (0.38) | PARP14TP53MEN1KMT2AKDM4E | |
| SCHEMBL11144647 | 0.81 | RAB9A (0.43) | TP53MEN1KMT2AADORA1ALDH1A1 | |
| SCHEMBL11344205 | 0.81 | TP53 (0.41) | TP53MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL11144388 | 0.80 | MEN1 (0.40) | PARP14TP53MEN1KMT2ADYRK1A | |
| SCHEMBL11151333 | 0.80 | MAPT (0.39) | TP53MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0005357-B1 | N-(BENZOTHIENOPYRAZOL)-AMIDES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-02-09 | — | — | EP | disclosed |
| EP-0005357-A1 | N-(Benzothienopyrazol)-amides and pharmaceutical compositions containing them | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-11-14 | — | — | EP | disclosed |
| US-4140785-A | N-(benzothienopyrazol)amide antirhinoviral agents | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-02-20 | — | — | US | disclosed |