Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | ESRRA | P11474 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29522175 | 0.81 | KDM4E (0.71) | KDM4EALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL260429 | 0.81 | KDM4E (0.71) | KDM4EALDH1A1GAAKMT2AMEN1 | |
| Hydrogen Sulfide SCHEMBL27456819 | 0.80 | KDM4E (0.69) | KDM4EALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL27567335 | 0.80 | KDM4E (0.69) | KDM4EALDH1A1GAAKMT2AMEN1 | |
| Hydrazine SCHEMBL28848708 | 0.80 | KDM4E (0.69) | KDM4EALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL11165947 | 0.78 | MEN1 (0.57) | KDM4EALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9617102 | 0.78 | HPGD (0.50) | KDM4EALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL11159755 | 0.78 | ALDH1A1 (0.51) | KDM4EALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL11158772 | 0.78 | ALDH1A1 (0.49) | KDM4EALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL7815135 | 0.77 | ADRA2C (0.59) | KDM4EALDH1A1GAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0017484-B1 | 2-IMIDAZOLINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND THE PHARMACEUTICAL COMPOSITION OF THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-04-06 | — | — | EP | disclosed |
| EP-0017484-A1 | 2-Imidazoline derivatives, process for the preparation thereof and the pharmaceutical composition of the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-10-15 | — | — | EP | disclosed |