Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4442336 | 0.92 | LMNA (0.58) | PDE7AMEN1KMT2ALMNAPOLB | |
| SCHEMBL4965383 | 0.89 | PDE7A (0.63) | PDE7AMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL4439447 | 0.88 | TDP1 (0.53) | PDE7AMEN1KMT2ALMNAPOLB | |
| SCHEMBL9185260 | 0.86 | ALDH1A1 (0.64) | MEN1KMT2ALMNASMN1; SMN2TDP1 | |
| SCHEMBL22114316 | 0.85 | HPGD (0.56) | PDE7AMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL28325585 | 0.84 | PDE7A (0.57) | PDE7AMEN1KMT2ALMNAPOLB | |
| SCHEMBL28831074 | 0.82 | PDE7A (0.52) | PDE7AMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL11511746 | 0.82 | PDE7A (0.71) | PDE7AMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL22069746 | 0.82 | PDE7A (0.58) | PDE7AMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL10756271 | 0.81 | S1PR4 (0.56) | PDE7ALMNAPOLBSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4401461-A | PRE- AND POSTEMERGENCE HERBICIDES; RICE | ROHM AND HAAS COMPANY (US) | 1983-08-30 | — | — | US | disclosed |
| US-4039588-A | ALKOXY, AMINO, HALO-, OR CYANO-SUBSTITUTED | ROHM AND HAAS COMPANY (US) | 1977-08-02 | — | — | US | disclosed |