Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | MGLL | Q99685 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 6/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | CRHBP | P24387 | 1/20 | 0.54 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11128203 | 0.88 | RAB9A (0.59) | LMNAMAPK1MGLLSMN1; SMN2RAB9A | |
| SCHEMBL11154096 | 0.85 | RAB9A (0.61) | MAPTLMNAHSD17B10SMN1; SMN2RAB9A | |
| SCHEMBL9340695 | 0.82 | SMN1; SMN2 (0.67) | MAPTLMNAMAPK1HSD17B10SMN1; SMN2 | |
| SCHEMBL10801844 | 0.81 | SIRT2 (0.56) | RAB9AKMT2ASIRT2NR1H4 | |
| SCHEMBL10805699 | 0.81 | SIRT2 (0.58) | MGLLRAB9AKMT2ASIRT2NR1H4 | |
| Desmedipham SCHEMBL4895813 | 0.80 | MAPK1 (0.68) | MAPTLMNAMAPK1HSD17B10SMN1; SMN2 | |
| Desmedipham SCHEMBL55084 | 0.80 | MAPK1 (0.68) | MAPTLMNAMAPK1HSD17B10SMN1; SMN2 | |
| Desmedipham SCHEMBL29516752 | 0.80 | MAPK1 (0.68) | MAPTLMNAMAPK1HSD17B10SMN1; SMN2 | |
| SCHEMBL13812777 | 0.79 | SIRT2 (0.59) | LMNAMEN1KMT2ASIRT2NR1H4 | |
| SCHEMBL4108576 | 0.79 | MAPK1 (0.74) | MAPTLMNAMAPK1HSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4405358-A | Aralkylaniline derivatives, and herbicides which contain these compounds | BASF AKTIENGESELLSCHAFT (DE) | 1983-09-20 | — | — | US | disclosed |