Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.57 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1142086 | 0.86 | LTA4H (0.64) | RAB9ASMN1; SMN2NR1H4USP2NPC1 | |
| SCHEMBL11128203 | 0.85 | RAB9A (0.59) | RAB9ASMN1; SMN2SIRT2NR1H4USP2 | |
| SCHEMBL1141794 | 0.85 | LMNA (0.61) | RAB9ASMN1; SMN2NR1H4NPC1GAA | |
| SCHEMBL11159873 | 0.85 | MAPT (0.60) | RAB9ASMN1; SMN2SIRT2NR1H4NPC1 | |
| SCHEMBL13652612 | 0.83 | MTNR1A (0.57) | RAB9ASMN1; SMN2NPC1GAAL3MBTL1 | |
| SCHEMBL10801844 | 0.83 | SIRT2 (0.56) | RAB9ASIRT2NR1H4USP2 | |
| SCHEMBL10805699 | 0.83 | SIRT2 (0.58) | RAB9ASIRT2NR1H4 | |
| SCHEMBL1142037 | 0.82 | HTT (0.72) | RAB9ASMN1; SMN2NR1H4NPC1GAA | |
| SCHEMBL9799045 | 0.80 | RAB9A (0.53) | RAB9ASMN1; SMN2SIRT2NR1H4USP2 | |
| SCHEMBL13652640 | 0.80 | THRB (0.55) | RAB9ASMN1; SMN2NR1H4NPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-55055148-A | — | — | None | — | — | JP | disclosed |
| US-4405358-A | Aralkylaniline derivatives, and herbicides which contain these compounds | BASF AKTIENGESELLSCHAFT (DE) | 1983-09-20 | — | — | US | disclosed |
| JP-S5555148-A | SUBSTITUTED ANILINE DERIVATIVE, ITS PREPARATION, HERBICIDE AND FUNGICIDE COMPRISING IT | SUMITOMO CHEM CO LTD | 1980-04-22 | — | — | JP | disclosed |