Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11477554 | 0.86 | MAPT (0.44) | MAPTLMNATP53RXFP1POLB | |
| Fluquazone SCHEMBL43464 | 0.86 | MAPT (0.58) | MAPTLMNATP53RXFP1 | |
| SCHEMBL11160129 | 0.86 | NR1I2 (0.50) | MAPTLMNAPTGDR2TP53 | |
| SCHEMBL11460555 | 0.86 | MAPT (0.53) | MAPTLMNATP53PTGER1 | |
| SCHEMBL11162361 | 0.85 | LMNA (0.54) | MAPTLMNATP53RXFP1POLB | |
| SCHEMBL11160051 | 0.83 | CASR (0.59) | MAPTLMNAPTGDR2TP53 | |
| SCHEMBL11163429 | 0.82 | L3MBTL1 (0.53) | MAPTLMNAPOLB | |
| SCHEMBL11638587 | 0.81 | PLK1 (0.46) | MAPTLMNATP53PTGER1RXFP1 | |
| SCHEMBL11459543 | 0.80 | PDE3B (0.47) | MAPTLMNATP53 | |
| SCHEMBL11479018 | 0.79 | RXFP1 (0.51) | MAPTLMNATP53RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4202895-A | 1-Polyhaloalkyl-2(1H)-quinazolinone derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-05-13 | — | — | US | disclosed |