SCHEMBL11166176

SCHEMBL11166176

Cc1nc(Br)oc1C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.37
ALDH1A1 P00352 5/20 0.36
HPGD P15428 4/20 0.36
TSHR P16473 2/20 0.36
GAA P10253 1/20 0.35
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
RXFP1 Q9HBX9 1/20 0.33
KDM4E B2RXH2 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MCL1 Q07820 2/20 0.32
GPR35 Q9HC97 1/20 0.32
MAPT P10636 3/20 0.32
HTT P42858 3/20 0.32
HSD17B10 Q99714 3/20 0.32
USP2 O75604 2/20 0.32
POLB P06746 2/20 0.32
GABRP O00591 1/20 0.31
GABRD O14764 1/20 0.31
GABRA1 P14867 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20855357 0.83 POLB (0.37) ALDH1A1HPGDTSHRGAAKDM4E
SCHEMBL22308295 0.79 ALDH1A1 (0.50) ALDH1A1HPGDMEN1KMT2AKDM4E
SCHEMBL11164366 0.77 TARBP2 (0.42) CYP1A2ALDH1A1HPGDGAAKDM4E
SCHEMBL286999 0.76 HSD17B10 (0.47) CYP1A2ALDH1A1HPGDTSHRGAA
SCHEMBL19556289 0.75 GABRP (0.36) CYP1A2GAAMEN1KMT2AGABRP
Hydrochloric Acid SCHEMBL10496189 0.74 HSD17B10 (0.46) CYP1A2ALDH1A1HPGDTSHRGAA
SCHEMBL11163237 0.73 CYP1A2 (0.37) CYP1A2ALDH1A1HPGDTSHRGAA
SCHEMBL11173035 0.73 ALDH1A1 (0.45) CYP1A2ALDH1A1HPGDTSHRGAA
SCHEMBL2714738 0.73 GABRP (0.39) CYP1A2ALDH1A1HPGDTSHRGAA
SCHEMBL13366301 0.73 GAA (0.39) CYP1A2ALDH1A1HPGDTSHRGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0027020-B1 2-SUBSTITUTED-4-ALKYL OR TRIHALOALKYL-5-OXAZOLECARBOXYLIC ACID DERIVATIVES, THEIR USE AS SAFENING AGENTS AND HERBICIDAL COMPOSITIONS CONTAINING THEM MONSANTO COMPANY (US) 1983-04-13 EP claimed