Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DBH | P09172 | 2/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | COMT | P21964 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5906264 | 0.70 | TLR9 (0.40) | MMP2POLBALDH1A1MAPTGAA | |
| SCHEMBL11168899 | 0.64 | — | — | |
| SCHEMBL6152348 | 0.63 | OPRM1 (0.38) | ALDH1A1KMT2AMEN1CYP2C9 | |
| SCHEMBL13379626 | 0.61 | CA12 (0.48) | GPR55ALDH1A1AKR1B1MAPTRAB9A | |
| SCHEMBL6614069 | 0.59 | CYP2C9 (0.35) | MMP2POLBALDH1A1MAPTGAA | |
| SCHEMBL8773331 | 0.59 | OPRM1 (0.35) | KMT2AMEN1CYP2C9 | |
| SCHEMBL3674004 | 0.58 | POLB (0.44) | MMP2POLBGPR55ALDH1A1MAPT | |
| Phenol SCHEMBL28096443 | 0.57 | TDP1 (0.48) | DBHMMP2ALDH1A1MAPTRAB9A | |
| SCHEMBL143060 | 0.57 | LMNA (0.42) | MMP2POLBGPR55ALDH1A1MAPT | |
| SCHEMBL10893354 | 0.54 | OPRM1 (0.34) | MMP2ALDH1A1MAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4376733-A | Preparation of oxacycloalkenones | FRIMER ARYEH | 1983-03-15 | — | — | US | disclosed |