Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1116561 | 1.00 | HSD11B1 (0.38) | HSD11B1HSD11B2 | |
| SCHEMBL706564 | 0.91 | HSD11B1 (0.46) | HSD11B1HSD11B2 | |
| SCHEMBL1118091 | 0.88 | HSD11B1 (0.35) | HSD11B1HSD11B2 | |
| SCHEMBL703066 | 0.86 | HSD11B1 (0.42) | HSD11B1 | |
| SCHEMBL16456994 | 0.82 | HSD11B1 (0.34) | HSD11B1 | |
| SCHEMBL1116577 | 0.79 | HSD11B1 (0.43) | HSD11B1HSD11B2 | |
| SCHEMBL708623 | 0.76 | HSD11B1 (0.34) | HSD11B1HSD11B2 | |
| SCHEMBL1116618 | 0.74 | HSD11B1 (0.51) | HSD11B1HSD11B2 | |
| SCHEMBL705603 | 0.73 | HSD11B1 (0.42) | HSD11B1 | |
| SCHEMBL705598 | 0.73 | HSD11B1 (0.42) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2280970-A1 | IMIDAZOLIDINONE DERIVATIVES AS 11B-HSD1 INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2011-02-09 | — | — | EP | disclosed |
| WO-2009132986-A1 | IMIDAZOLIDINONE DERIVATIVES AS 11B-HSD1 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-11-05 | — | — | WO | disclosed |