Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.90 |
| ▸ | DRD2 | P14416 | 1/20 | 0.90 |
| ▸ | PTGES | O14684 | 9/20 | 0.77 |
| ▸ | ALOX5 | P09917 | 8/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.55 |
| ▸ | CDK2 | P24941 | 4/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | AURKA | O14965 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11245260 | 0.94 | KDM4E (0.90) | KDM4EDRD2PTGESALOX5ALDH1A1 | |
| Lonazolac SCHEMBL25221 | 0.94 | KDM4E (1.00) | KDM4EDRD2PTGESALOX5ALDH1A1 | |
| SCHEMBL11258042 | 0.94 | KDM4E (0.79) | KDM4EDRD2PTGESALOX5ALDH1A1 | |
| Lonazolac SCHEMBL1478078 | 0.93 | KDM4E (0.97) | KDM4EDRD2PTGESALOX5ALDH1A1 | |
| Lonazolac SCHEMBL287156 | 0.93 | KDM4E (0.97) | KDM4EDRD2PTGESALOX5ALDH1A1 | |
| SCHEMBL11160338 | 0.90 | KDM4E (0.74) | KDM4EDRD2PTGESALOX5ALDH1A1 | |
| SCHEMBL10877279 | 0.85 | KDM4E (0.83) | KDM4EDRD2PTGESALOX5ALDH1A1 | |
| SCHEMBL11153037 | 0.84 | KDM4E (0.76) | KDM4EDRD2PTGESALOX5ALDH1A1 | |
| SCHEMBL12608902 | 0.84 | KDM4E (0.81) | KDM4EDRD2PTGESALOX5ALDH1A1 | |
| SCHEMBL3475488 | 0.84 | KDM4E (0.81) | KDM4EDRD2PTGESALOX5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0094555-A1 | Substituted 2-pyrazolin-4-acetic acids, process for their preparation, their use and agents containing them | Kohl, Bernhard, Dr. (DE) | 1983-11-23 | — | — | EP | disclosed |