Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.81 |
| ▸ | DRD2 | P14416 | 1/20 | 0.81 |
| ▸ | PTGES | O14684 | 9/20 | 0.76 |
| ▸ | ALOX5 | P09917 | 8/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.60 |
| ▸ | CDK2 | P24941 | 3/20 | 0.60 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | AURKA | O14965 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10877279 | 0.91 | KDM4E (0.83) | KDM4EDRD2PTGESALOX5ALDH1A1 | |
| Lonazolac SCHEMBL25221 | 0.90 | KDM4E (1.00) | KDM4EDRD2PTGESALOX5ALDH1A1 | |
| Lonazolac SCHEMBL287156 | 0.88 | KDM4E (0.97) | KDM4EDRD2PTGESALOX5ALDH1A1 | |
| Lonazolac SCHEMBL1478078 | 0.88 | KDM4E (0.97) | KDM4EDRD2PTGESALOX5ALDH1A1 | |
| SCHEMBL12608902 | 0.87 | KDM4E (0.81) | KDM4EDRD2PTGESALOX5ALDH1A1 | |
| Lonazolac SCHEMBL10577835 | 0.86 | PTGES (1.00) | KDM4EDRD2PTGESALOX5ALDH1A1 | |
| SCHEMBL11257500 | 0.85 | KDM4E (0.77) | KDM4EDRD2PTGESALOX5ALDH1A1 | |
| SCHEMBL11245260 | 0.84 | KDM4E (0.90) | KDM4EDRD2PTGESALOX5ALDH1A1 | |
| SCHEMBL11253903 | 0.84 | KDM4E (0.76) | KDM4EDRD2PTGESALOX5ALDH1A1 | |
| SCHEMBL11166545 | 0.84 | KDM4E (0.90) | KDM4EDRD2PTGESALOX5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009124371-A9 | NOVEL COMPOUNDS DERIVED FROM TAURINE, PROCESS OF THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE | EMS S. A. (BR) | 2010-12-02 | — | — | WO | claimed |
| WO-2009124371-A2 | NOVEL COMPOUNDS DERIVED FROM TAURINE, PROCESS OF THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE | EMS S. A. (BR) | 2009-10-15 | — | — | WO | claimed |
| US-4325962-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIDYRETICS | BYK-GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-04-20 | — | — | US | disclosed |
| US-4146721-A | ANALGESICS, ANTIINFLAMMATORY AGENTS AND ANTIPYRETICS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1979-03-27 | — | — | US | disclosed |